Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation

Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation

BackgroundGastric cancer (GC) is ranked as the third leading cause of cancer-related mortality worldwide. 1,2,3,4,6-Pentagalloyl-β-D-glucose (β-PGG) has various pharmacological activities and has been shown to suppress cancer development. However, the mechanism by which β-PGG inhibits gastric cancer...

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Bibliographic Details
Main Authors:	Jing-hui Bi, Yu-han Jiang, Shi-jie Ye, Min-rui Wu, Yang Yi, Hong-xun Wang, Li-mei Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Oncology
Subjects:	β-PGG gastric cancer network pharmacology mechanism p53 signaling pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.934958/full

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