Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats
Understanding the correlations between dietary fibers' physical properties and postprandial appetite response helps to design novel functional products with satiety enhancing capability. In the present study, the partially degraded konjac glucomannan (Pd-KGM) was obtained by applying the hetero...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-01-01
|
| Series: | Food Hydrocolloids for Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667025921000182 |
| _version_ | 1819096820087783424 |
|---|---|
| author | Longchen Shang Tingyang Ai Jing Li Bin Li |
| author_facet | Longchen Shang Tingyang Ai Jing Li Bin Li |
| author_sort | Longchen Shang |
| collection | DOAJ |
| description | Understanding the correlations between dietary fibers' physical properties and postprandial appetite response helps to design novel functional products with satiety enhancing capability. In the present study, the partially degraded konjac glucomannan (Pd-KGM) was obtained by applying the heterogeneous hygrothermal degradation method, and its flow behavior was studied for guiding the preparation of sols with equi-concentration but differed in viscosity. The appetite-regulating effects derived from the sol viscosity were explored by monitoring the appetite hormone response and the feeding behavior of rats after they were given the Pd-KGM sols. By lowering the secretion of ghrelin, elevating the plasma concentration of GLP-1, PYY3–36, and CCK-8, and stabilizing blood glucose and insulin fluctuation, the sol with increased viscosity showed an improved satiety-enhancing capability. Moreover, the transition point from feeding to resting was advanced in rats given a more viscous sol, resulting in a significantly decreased feed intake (p < 0.05). We further explored the correlations between sol viscosity and its nutritional effects relating to appetite regulation depending on the quantitative data obtained in this study. Excluding the plasma glucose and CCK-8, a strong linear correlation (Pearson coefficient > 0.7) emerged between the appetite hormone and the sol viscosity, especially for the GLP-1, which its Pearson coefficient was 0.946, indicating a very highly correlated relationship between them. Thus, these results revealed the feasibility of regulating appetite by taking advantage of sol viscosity. |
| first_indexed | 2024-12-22T00:05:16Z |
| format | Article |
| id | doaj.art-2646e6f7064a4c73b966b7b253264353 |
| institution | Directory Open Access Journal |
| issn | 2667-0259 |
| language | English |
| last_indexed | 2024-12-22T00:05:16Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Hydrocolloids for Health |
| spelling | doaj.art-2646e6f7064a4c73b966b7b2532643532022-12-21T18:45:35ZengElsevierFood Hydrocolloids for Health2667-02592021-01-011100026Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of ratsLongchen Shang0Tingyang Ai1Jing Li2Bin Li3College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Ministry of Education, ChinaCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Ministry of Education, ChinaCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Ministry of Education, ChinaCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Ministry of Education, China; Corresponding author at: College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.Understanding the correlations between dietary fibers' physical properties and postprandial appetite response helps to design novel functional products with satiety enhancing capability. In the present study, the partially degraded konjac glucomannan (Pd-KGM) was obtained by applying the heterogeneous hygrothermal degradation method, and its flow behavior was studied for guiding the preparation of sols with equi-concentration but differed in viscosity. The appetite-regulating effects derived from the sol viscosity were explored by monitoring the appetite hormone response and the feeding behavior of rats after they were given the Pd-KGM sols. By lowering the secretion of ghrelin, elevating the plasma concentration of GLP-1, PYY3–36, and CCK-8, and stabilizing blood glucose and insulin fluctuation, the sol with increased viscosity showed an improved satiety-enhancing capability. Moreover, the transition point from feeding to resting was advanced in rats given a more viscous sol, resulting in a significantly decreased feed intake (p < 0.05). We further explored the correlations between sol viscosity and its nutritional effects relating to appetite regulation depending on the quantitative data obtained in this study. Excluding the plasma glucose and CCK-8, a strong linear correlation (Pearson coefficient > 0.7) emerged between the appetite hormone and the sol viscosity, especially for the GLP-1, which its Pearson coefficient was 0.946, indicating a very highly correlated relationship between them. Thus, these results revealed the feasibility of regulating appetite by taking advantage of sol viscosity.http://www.sciencedirect.com/science/article/pii/S2667025921000182Konjac glucomannanViscosityAppetiteFood intakeCorrelation |
| spellingShingle | Longchen Shang Tingyang Ai Jing Li Bin Li Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats Food Hydrocolloids for Health Konjac glucomannan Viscosity Appetite Food intake Correlation |
| title | Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| title_full | Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| title_fullStr | Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| title_full_unstemmed | Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| title_short | Correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| title_sort | correlations between sol viscosity of the partially degraded konjac glucomannan and appetite response of rats |
| topic | Konjac glucomannan Viscosity Appetite Food intake Correlation |
| url | http://www.sciencedirect.com/science/article/pii/S2667025921000182 |
| work_keys_str_mv | AT longchenshang correlationsbetweensolviscosityofthepartiallydegradedkonjacglucomannanandappetiteresponseofrats AT tingyangai correlationsbetweensolviscosityofthepartiallydegradedkonjacglucomannanandappetiteresponseofrats AT jingli correlationsbetweensolviscosityofthepartiallydegradedkonjacglucomannanandappetiteresponseofrats AT binli correlationsbetweensolviscosityofthepartiallydegradedkonjacglucomannanandappetiteresponseofrats |