Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study
Purpose: Currently, the prediction of progressive ischemic stroke (PIS) caused by large proximal artery occlusion (LVO) is not well developed. The main aim of the study is to check the effectiveness of endovascular thrombectomy(EVT) in patients with PIS and LVO in the anterior circulation. Methods:...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Interdisciplinary Neurosurgery |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751923001354 |
| _version_ | 1827793465464848384 |
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| author | Yanchun Wang Jianzhong Shu Minghua Tao Mingshan Tang Chende Pan Dinghao Zhen Jie Wang |
| author_facet | Yanchun Wang Jianzhong Shu Minghua Tao Mingshan Tang Chende Pan Dinghao Zhen Jie Wang |
| author_sort | Yanchun Wang |
| collection | DOAJ |
| description | Purpose: Currently, the prediction of progressive ischemic stroke (PIS) caused by large proximal artery occlusion (LVO) is not well developed. The main aim of the study is to check the effectiveness of endovascular thrombectomy(EVT) in patients with PIS and LVO in the anterior circulation. Methods: This multicenter retrospective cohort study involved two comprehensive stroke centres having two therapeutic approaches to manage patients with minor, mild, or acute ischemic stroke harbouring LVO. Some patients who experienced early neurologic deterioration (END) were either given the best medical care (BMM) or immediate rescue endovascular thrombectomy (RET) followed by BMM. Clinical outcomes, including good prognosis defined as 90-day modified Ranking Scale (mRS) ≤ 2, mortality, and symptomatic intracerebral hemorrhagic (sICH) rate were compared between two groups. Results: The study included 103 patients, including 48 patients in the RET + BMM group and 55 patients in the BMM group, and each group included 35 patients after propensity score matching. Compared to the BMM group, RET-treated patients had lower 90-day mRS scores at discharge (57.14% vs. 37.14%, p < 0.001). No significant differences in mortality (p = 0.315) and symptomatic intracranial haemorrhage (p = 0.487) were found. Similar results were obtained after propensity score matching. Conclusion: RET appears to be safe and feasible in patients with PIS due to LVO within 24–72 h. Further prospective, clinical, randomized controlled studies are warranted to validate these findings. |
| first_indexed | 2024-03-11T18:18:50Z |
| format | Article |
| id | doaj.art-264716a47ed747d7bf81febce4dcad8b |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-03-11T18:18:50Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-264716a47ed747d7bf81febce4dcad8b2023-10-16T04:12:29ZengElsevierInterdisciplinary Neurosurgery2214-75192023-12-0134101852Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort studyYanchun Wang0Jianzhong Shu1Minghua Tao2Mingshan Tang3Chende Pan4Dinghao Zhen5Jie Wang6Department of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, ChinaDepartment of Neurology, Chongqing Hospital of Traditional Chinese Medicine, No.6, Seventh Branch Road, Panxi, Jiangbei District 400011, Chongqing, ChinaDepartment of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, ChinaDepartment of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, ChinaDepartment of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, ChinaDepartment of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, ChinaDepartment of Neurology, Banan Hospital of Chongqing Medical University and People's Hospital of Chongqing Banan District, No. 659, Yunan Road, Banan District, Chongqing 401320, China; Corresponding author.Purpose: Currently, the prediction of progressive ischemic stroke (PIS) caused by large proximal artery occlusion (LVO) is not well developed. The main aim of the study is to check the effectiveness of endovascular thrombectomy(EVT) in patients with PIS and LVO in the anterior circulation. Methods: This multicenter retrospective cohort study involved two comprehensive stroke centres having two therapeutic approaches to manage patients with minor, mild, or acute ischemic stroke harbouring LVO. Some patients who experienced early neurologic deterioration (END) were either given the best medical care (BMM) or immediate rescue endovascular thrombectomy (RET) followed by BMM. Clinical outcomes, including good prognosis defined as 90-day modified Ranking Scale (mRS) ≤ 2, mortality, and symptomatic intracerebral hemorrhagic (sICH) rate were compared between two groups. Results: The study included 103 patients, including 48 patients in the RET + BMM group and 55 patients in the BMM group, and each group included 35 patients after propensity score matching. Compared to the BMM group, RET-treated patients had lower 90-day mRS scores at discharge (57.14% vs. 37.14%, p < 0.001). No significant differences in mortality (p = 0.315) and symptomatic intracranial haemorrhage (p = 0.487) were found. Similar results were obtained after propensity score matching. Conclusion: RET appears to be safe and feasible in patients with PIS due to LVO within 24–72 h. Further prospective, clinical, randomized controlled studies are warranted to validate these findings.http://www.sciencedirect.com/science/article/pii/S2214751923001354Rescue endovascular thrombectomyProgressive ischemic strokeLarge vessel occlusionPropensity score matching |
| spellingShingle | Yanchun Wang Jianzhong Shu Minghua Tao Mingshan Tang Chende Pan Dinghao Zhen Jie Wang Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study Interdisciplinary Neurosurgery Rescue endovascular thrombectomy Progressive ischemic stroke Large vessel occlusion Propensity score matching |
| title | Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study |
| title_full | Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study |
| title_fullStr | Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study |
| title_full_unstemmed | Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study |
| title_short | Rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24–72 h: A retrospective propensity score matched cohort study |
| title_sort | rescue endovascular thrombectomy in patients with progressive ischemic stroke within 24 72 h a retrospective propensity score matched cohort study |
| topic | Rescue endovascular thrombectomy Progressive ischemic stroke Large vessel occlusion Propensity score matching |
| url | http://www.sciencedirect.com/science/article/pii/S2214751923001354 |
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