Correlation of N-glycan dynamics and interaction network with allosteric antigen binding and Fc receptor recognition
Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may also regulate antigen recognition. In the antibody drug development, glycosylation patterns affect antibody drug characteristics and quality control. In order to provide a global feature of N-glycan int...
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2021-04-01
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| Series: | Exploration of Immunology |
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| Online Access: | https://www.explorationpub.com/Journals/ei/Article/10034 |