ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE
<p>Background. This study was designed to evaluate the impact of various prognostic factors on long-term survival and event free survival after allogeneic hematopoietic stem cell transplantation for patients with acute leukemia.</p><p>Methods and patients. Between years 1989 and 20...
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| Format: | Article |
| Language: | English |
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Slovenian Medical Association
2004-12-01
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| Series: | Zdravniški Vestnik |
| Subjects: | |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/2423 |
| _version_ | 1811284348925640704 |
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| author | Jože Pretnar Irena Preložnik Zupan |
| author_facet | Jože Pretnar Irena Preložnik Zupan |
| author_sort | Jože Pretnar |
| collection | DOAJ |
| description | <p>Background. This study was designed to evaluate the impact of various prognostic factors on long-term survival and event free survival after allogeneic hematopoietic stem cell transplantation for patients with acute leukemia.</p><p>Methods and patients. Between years 1989 and 2002 44 patients with acute leukemia (30 with AML and 14 with ALL) were transplanted. Survival curves using the Kaplan-Meier method were calculated for patients transplanted with two different sources of stem cells – bone marrow and peripheral blood and separately for patients with female donor.</p><p>Results. Estimated 10 years survival for AML is 43% and 64% for ALL patients which is not statistically different. There are no significant differences in outcome regarding source of stem cells and in donors’ gender.</p><p>Conclusions. To conclude, our results show that neither source of stem cells nor donor’s gender has impact on the long-term survival after hematopoietic stem cell transplantation. As published previously patients transplanted beyond the first remission have significantly worse outcome.<br /><br /></p> |
| first_indexed | 2024-04-13T02:27:22Z |
| format | Article |
| id | doaj.art-26494f3531a04fb0982e1a2b7ba55b06 |
| institution | Directory Open Access Journal |
| issn | 1318-0347 1581-0224 |
| language | English |
| last_indexed | 2024-04-13T02:27:22Z |
| publishDate | 2004-12-01 |
| publisher | Slovenian Medical Association |
| record_format | Article |
| series | Zdravniški Vestnik |
| spelling | doaj.art-26494f3531a04fb0982e1a2b7ba55b062022-12-22T03:06:43ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242004-12-017301892ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCEJože Pretnar0Irena Preložnik Zupan1Klinični oddelek za hematologijo Interna klinika Klinični center Zaloška 7 1525 LjubljanaKlinični oddelek za hematologijo Interna klinika Klinični center Zaloška 7 1525 Ljubljana<p>Background. This study was designed to evaluate the impact of various prognostic factors on long-term survival and event free survival after allogeneic hematopoietic stem cell transplantation for patients with acute leukemia.</p><p>Methods and patients. Between years 1989 and 2002 44 patients with acute leukemia (30 with AML and 14 with ALL) were transplanted. Survival curves using the Kaplan-Meier method were calculated for patients transplanted with two different sources of stem cells – bone marrow and peripheral blood and separately for patients with female donor.</p><p>Results. Estimated 10 years survival for AML is 43% and 64% for ALL patients which is not statistically different. There are no significant differences in outcome regarding source of stem cells and in donors’ gender.</p><p>Conclusions. To conclude, our results show that neither source of stem cells nor donor’s gender has impact on the long-term survival after hematopoietic stem cell transplantation. As published previously patients transplanted beyond the first remission have significantly worse outcome.<br /><br /></p>http://vestnik.szd.si/index.php/ZdravVest/article/view/2423acute leukemiaadult patienthematopoietic stem cellallogeneic stem cell transplantation |
| spellingShingle | Jože Pretnar Irena Preložnik Zupan ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE Zdravniški Vestnik acute leukemia adult patient hematopoietic stem cell allogeneic stem cell transplantation |
| title | ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE |
| title_full | ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE |
| title_fullStr | ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE |
| title_full_unstemmed | ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE |
| title_short | ALLOGENEIC STEM CELL TRANSPLANTATION FOR ADULT PATIENTS WITH ACUTE LEUKEMIA – 14 YEARS EXPERIENCE |
| title_sort | allogeneic stem cell transplantation for adult patients with acute leukemia 14 years experience |
| topic | acute leukemia adult patient hematopoietic stem cell allogeneic stem cell transplantation |
| url | http://vestnik.szd.si/index.php/ZdravVest/article/view/2423 |
| work_keys_str_mv | AT jozepretnar allogeneicstemcelltransplantationforadultpatientswithacuteleukemia14yearsexperience AT irenapreloznikzupan allogeneicstemcelltransplantationforadultpatientswithacuteleukemia14yearsexperience |