METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION
Results of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». Th...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/301 |
| _version_ | 1797875019747950592 |
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| author | N. N. Krylov E. V. Kompantseva |
| author_facet | N. N. Krylov E. V. Kompantseva |
| author_sort | N. N. Krylov |
| collection | DOAJ |
| description | Results of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». The assay method for the sum of flavonoids in the dry extracts from this raw material and tablets «Ginkgotropil-forte» is developed. Justification of limit of flavonoid content in tablets «Ginkgotropil-forte» is presented and the limit is not less than 6 mg, based on the average weight of the tablet. The proposed method was validated for specificity, linearity, precision and accuracy. |
| first_indexed | 2024-04-10T01:39:56Z |
| format | Article |
| id | doaj.art-264a36e3e50f4d13aa93e687e9dc4b1a |
| institution | Directory Open Access Journal |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| last_indexed | 2024-04-10T01:39:56Z |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj.art-264a36e3e50f4d13aa93e687e9dc4b1a2023-03-13T09:13:58ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0103146151301METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTIONN. N. Krylov0E. V. Kompantseva1Пятигорский медико-фармацевтический институт - филиал ГБОУ ВПО ВолгГМУ Минздрава РоссииПятигорский медико-фармацевтический институт - филиал ГБОУ ВПО ВолгГМУ Минздрава РоссииResults of development of differential spectrophotometry method for determination of the total flavonoids assay in tablets containing dry extracts of ginkgo biloba are presented. Total flavonoid assay in leaves of ginkgo biloba and grass meadowsweet is preliminary presented by LLC «Vitaukt-Prom». The assay method for the sum of flavonoids in the dry extracts from this raw material and tablets «Ginkgotropil-forte» is developed. Justification of limit of flavonoid content in tablets «Ginkgotropil-forte» is presented and the limit is not less than 6 mg, based on the average weight of the tablet. The proposed method was validated for specificity, linearity, precision and accuracy.https://www.pharmjournal.ru/jour/article/view/301таблеткифлавоноидыгинкго двулопастныйлабазник вязолистныйвалидациядифференциальная спектрофотометрия |
| spellingShingle | N. N. Krylov E. V. Kompantseva METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION Разработка и регистрация лекарственных средств таблетки флавоноиды гинкго двулопастный лабазник вязолистный валидация дифференциальная спектрофотометрия |
| title | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_full | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_fullStr | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_full_unstemmed | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_short | METHOD DEVELOPMENT AND VALIDATION OF TOTAL FLAVONOIDS ASSAY IN TABLETS WITH NOOTROPIC ACTION |
| title_sort | method development and validation of total flavonoids assay in tablets with nootropic action |
| topic | таблетки флавоноиды гинкго двулопастный лабазник вязолистный валидация дифференциальная спектрофотометрия |
| url | https://www.pharmjournal.ru/jour/article/view/301 |
| work_keys_str_mv | AT nnkrylov methoddevelopmentandvalidationoftotalflavonoidsassayintabletswithnootropicaction AT evkompantseva methoddevelopmentandvalidationoftotalflavonoidsassayintabletswithnootropicaction |