Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers

Existing preparation methods for microdroplets usually require offline measurements to characterize single microdroplets. Here, we report an optical method used to facilitate the controllable formation and real-time characterization of single microdroplets. The optical tweezer technique was used to...

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Main Authors: Shuai Li, Hanlin Zhang, Wenqiang Li, Yizhou Zhang, Xiaowen Gao, Haiqing Liu, Nan Li, Huizhu Hu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/13/10/1693
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author Shuai Li
Hanlin Zhang
Wenqiang Li
Yizhou Zhang
Xiaowen Gao
Haiqing Liu
Nan Li
Huizhu Hu
author_facet Shuai Li
Hanlin Zhang
Wenqiang Li
Yizhou Zhang
Xiaowen Gao
Haiqing Liu
Nan Li
Huizhu Hu
author_sort Shuai Li
collection DOAJ
description Existing preparation methods for microdroplets usually require offline measurements to characterize single microdroplets. Here, we report an optical method used to facilitate the controllable formation and real-time characterization of single microdroplets. The optical tweezer technique was used to capture and form a microdroplet at the center of the trap. The controllable growth and real-time characterization of the microdroplet was realized, respectively, by adjusting experimental parameters and by resolving the Raman spectra by fitting Mie scattering to the spike positions of the spectra during the controllable growth of microdroplets. The proposed method can be potentially applied in optical microlenses and virus detection.
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spelling doaj.art-264a39169e02445288c361e79ad6c41f2023-11-24T01:22:52ZengMDPI AGMicromachines2072-666X2022-10-011310169310.3390/mi13101693Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical TweezersShuai Li0Hanlin Zhang1Wenqiang Li2Yizhou Zhang3Xiaowen Gao4Haiqing Liu5Nan Li6Huizhu Hu7Quantum Sensing Center, Zhejiang Lab., Hangzhou 310000, ChinaState Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaQuantum Sensing Center, Zhejiang Lab., Hangzhou 310000, ChinaQuantum Sensing Center, Zhejiang Lab., Hangzhou 310000, ChinaIsvision (Hangzhou) Technology Co., Ltd., Hangzhou 310052, ChinaState Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaQuantum Sensing Center, Zhejiang Lab., Hangzhou 310000, ChinaExisting preparation methods for microdroplets usually require offline measurements to characterize single microdroplets. Here, we report an optical method used to facilitate the controllable formation and real-time characterization of single microdroplets. The optical tweezer technique was used to capture and form a microdroplet at the center of the trap. The controllable growth and real-time characterization of the microdroplet was realized, respectively, by adjusting experimental parameters and by resolving the Raman spectra by fitting Mie scattering to the spike positions of the spectra during the controllable growth of microdroplets. The proposed method can be potentially applied in optical microlenses and virus detection.https://www.mdpi.com/2072-666X/13/10/1693optical tweezersmicrodropletssinglecontrollable formationreal-time characterization
spellingShingle Shuai Li
Hanlin Zhang
Wenqiang Li
Yizhou Zhang
Xiaowen Gao
Haiqing Liu
Nan Li
Huizhu Hu
Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
Micromachines
optical tweezers
microdroplets
single
controllable formation
real-time characterization
title Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
title_full Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
title_fullStr Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
title_full_unstemmed Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
title_short Controllable Formation and Real-Time Characterization of Single Microdroplets Using Optical Tweezers
title_sort controllable formation and real time characterization of single microdroplets using optical tweezers
topic optical tweezers
microdroplets
single
controllable formation
real-time characterization
url https://www.mdpi.com/2072-666X/13/10/1693
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AT yizhouzhang controllableformationandrealtimecharacterizationofsinglemicrodropletsusingopticaltweezers
AT xiaowengao controllableformationandrealtimecharacterizationofsinglemicrodropletsusingopticaltweezers
AT haiqingliu controllableformationandrealtimecharacterizationofsinglemicrodropletsusingopticaltweezers
AT nanli controllableformationandrealtimecharacterizationofsinglemicrodropletsusingopticaltweezers
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