Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report
Thirty one - year - old female, a case of extensive gangrene of the skin due to systemic lupus erythematosis (SLE) with cytomegalovirus wound infection is presented as the fourth case of SLE and CNlv infection of the skin in the available literature. Diagnosis of SLE was confirmed by significant tit...
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2001-02-01
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| Series: | Indian Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778549 |
| _version_ | 1797271513567592448 |
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| author | M S Gopasetty P Kumar G Krishnanand G Arunkumar C Balachandran K G Bhaskara |
| author_facet | M S Gopasetty P Kumar G Krishnanand G Arunkumar C Balachandran K G Bhaskara |
| author_sort | M S Gopasetty |
| collection | DOAJ |
| description | Thirty one - year - old female, a case of extensive gangrene of the skin due to systemic lupus erythematosis (SLE) with cytomegalovirus wound infection is presented as the fourth case of SLE and CNlv infection of the skin in the available literature. Diagnosis of SLE was confirmed by significant titers of antinuclear antibodies, antibodies against double stranded DNA (anti ds DNA) and by demonstration of lupus band in the biopsy from the normal skin (by direct immunoflourescence technique). Diagnosis of cytomegalovirus (CMV) in the wound was made because ofthe presence of characteristic intranuclear inclusion bodies in the endothelial cells of the biopsy specimen. It was confirmed by detection of CMV antigen in the frozen section of the specimen by immunoflourescence technique and also by detection of antigen in the blood by ELISA.. Extensive gangrene of the skin in a case of SLE with CMV wound infection without systemic involvement makes this case very unusual. The cutaneous lesions associate with CMV infection is discussed. |
| first_indexed | 2024-03-07T14:05:42Z |
| format | Article |
| id | doaj.art-26506acd653847699c052283bc411381 |
| institution | Directory Open Access Journal |
| issn | 0970-0358 1998-376X |
| language | English |
| last_indexed | 2024-03-07T14:05:42Z |
| publishDate | 2001-02-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj.art-26506acd653847699c052283bc4113812024-03-06T23:40:46ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2001-02-01340101501910.1055/s-0043-1778549Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case reportM S Gopasetty0P Kumar1G Krishnanand2G Arunkumar3C Balachandran4K G Bhaskara5Department of Plastic Surgery & Burns, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaDepartment of Plastic Surgery & Burns, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaPathology, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaMicrobiology, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaSkin & VD, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaDepartment of Plastic Surgery & Burns, Kasturba Medical college, Manipal 576 119, Karnataka, IndiaThirty one - year - old female, a case of extensive gangrene of the skin due to systemic lupus erythematosis (SLE) with cytomegalovirus wound infection is presented as the fourth case of SLE and CNlv infection of the skin in the available literature. Diagnosis of SLE was confirmed by significant titers of antinuclear antibodies, antibodies against double stranded DNA (anti ds DNA) and by demonstration of lupus band in the biopsy from the normal skin (by direct immunoflourescence technique). Diagnosis of cytomegalovirus (CMV) in the wound was made because ofthe presence of characteristic intranuclear inclusion bodies in the endothelial cells of the biopsy specimen. It was confirmed by detection of CMV antigen in the frozen section of the specimen by immunoflourescence technique and also by detection of antigen in the blood by ELISA.. Extensive gangrene of the skin in a case of SLE with CMV wound infection without systemic involvement makes this case very unusual. The cutaneous lesions associate with CMV infection is discussed.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778549CMVskin infectionSLECutaneous gangrene |
| spellingShingle | M S Gopasetty P Kumar G Krishnanand G Arunkumar C Balachandran K G Bhaskara Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report Indian Journal of Plastic Surgery CMV skin infection SLE Cutaneous gangrene |
| title | Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report |
| title_full | Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report |
| title_fullStr | Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report |
| title_full_unstemmed | Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report |
| title_short | Systemic Lupus Erythematosis with Extensive Cutaneous Gangrene with Cutaneous Cytomegalovirus Infection : A case report |
| title_sort | systemic lupus erythematosis with extensive cutaneous gangrene with cutaneous cytomegalovirus infection a case report |
| topic | CMV skin infection SLE Cutaneous gangrene |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778549 |
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