Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex

Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex

<i>Plasmodium</i> species are protozoan parasites causing the deadly malaria disease. They have developed effective resistance mechanisms against most antimalarial medication, causing an urgent need to identify new antimalarial drug targets. Ideally, new drugs would be generated to speci...

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Bibliographic Details
Main Authors: Najeeb Ullah, Hina Andaleeb, Celestin Nzanzu Mudogo, Sven Falke, Christian Betzel, Carsten Wrenger
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
pyridoxal phosphate (PLP) synthase
Pdx1 and Pdx2
solution structure
protein–protein interactions
reversible oligomerization
drug discovery
Online Access:https://www.mdpi.com/1422-0067/21/17/5971

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