Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients

Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients

Nuzzo, Russo, Errico, D’Amico et al. investigate neuroinflammation in forty-eight pediatric spinal muscular atrophy patients before and after Nusinersen treatment. They find signatures of neuroinflammation that are specifically associated with severe disease and show that Nusinersen therapy has neur...

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Bibliographic Details
Main Authors: Tommaso Nuzzo, Rosita Russo, Francesco Errico, Adele D’Amico, Awet G. Tewelde, Mariangela Valletta, Amber Hassan, Michele Tosi, Chiara Panicucci, Claudio Bruno, Enrico Bertini, Angela Chambery, Livio Pellizzoni, Alessandro Usiello
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00256-2

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