A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion

Background: This study was done to evaluate remineralizing potential of bioactive glasses (BAGs) and amorphous calcium phosphate-casein phosphopeptide (ACP-CPP) on early enamel lesion. Materials and Methods: Twenty freshly extracted mandibular premolars were sectioned sagittally. The buccal half was...

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Main Authors: Udaya Kumar Palaniswamy, Neha Prashar, Mamta Kaushik, Surender Ram Lakkam, Shikha Arya, Swetha Pebbeti
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Dental Research Journal
Subjects:
Online Access:http://www.drjjournal.net/article.asp?issn=1735-3327;year=2016;volume=13;issue=4;spage=297;epage=302;aulast=Palaniswamy
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author Udaya Kumar Palaniswamy
Neha Prashar
Mamta Kaushik
Surender Ram Lakkam
Shikha Arya
Swetha Pebbeti
author_facet Udaya Kumar Palaniswamy
Neha Prashar
Mamta Kaushik
Surender Ram Lakkam
Shikha Arya
Swetha Pebbeti
author_sort Udaya Kumar Palaniswamy
collection DOAJ
description Background: This study was done to evaluate remineralizing potential of bioactive glasses (BAGs) and amorphous calcium phosphate-casein phosphopeptide (ACP-CPP) on early enamel lesion. Materials and Methods: Twenty freshly extracted mandibular premolars were sectioned sagittally. The buccal half was impregnated in acrylic resin blocks and treated with 37% phosphoric acid in liquid form, to demineralize enamel surface to simulate early enamel lesion. The samples were divided into two groups. The samples in Group I were treated with ACP-CPP (GC Tooth Mousse) and in Group II with BAG (Sensodyne Repair and Protect) and stored in saliva to prevent dehydration. The samples were tested for microhardness. The data obtained was analyzed using ANOVA post hoc multiple comparison and independent sample t- test and presented as a mean and standard deviation. Results: All the samples showed a decrease in the microhardness after demineralization. After application of remineralizing agents, Group II showed a highly significant increase in the microhardness (P < 0.05) after 10 days, while Group I showed a significant increase in microhardness after 15 days (P < 0.05). Conclusion: Both the remineralizing agents tested in this study can be considered effective in repair and prevention of demineralization. BAG showed better results initially, but eventually both have similar remineralizing potential.
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spelling doaj.art-26596ac3beee40638c6c71755c37d7122022-12-21T19:41:53ZengWolters Kluwer Medknow PublicationsDental Research Journal1735-33272008-02552016-01-0113429730210.4103/1735-3327.187872A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesionUdaya Kumar PalaniswamyNeha PrasharMamta KaushikSurender Ram LakkamShikha AryaSwetha PebbetiBackground: This study was done to evaluate remineralizing potential of bioactive glasses (BAGs) and amorphous calcium phosphate-casein phosphopeptide (ACP-CPP) on early enamel lesion. Materials and Methods: Twenty freshly extracted mandibular premolars were sectioned sagittally. The buccal half was impregnated in acrylic resin blocks and treated with 37% phosphoric acid in liquid form, to demineralize enamel surface to simulate early enamel lesion. The samples were divided into two groups. The samples in Group I were treated with ACP-CPP (GC Tooth Mousse) and in Group II with BAG (Sensodyne Repair and Protect) and stored in saliva to prevent dehydration. The samples were tested for microhardness. The data obtained was analyzed using ANOVA post hoc multiple comparison and independent sample t- test and presented as a mean and standard deviation. Results: All the samples showed a decrease in the microhardness after demineralization. After application of remineralizing agents, Group II showed a highly significant increase in the microhardness (P < 0.05) after 10 days, while Group I showed a significant increase in microhardness after 15 days (P < 0.05). Conclusion: Both the remineralizing agents tested in this study can be considered effective in repair and prevention of demineralization. BAG showed better results initially, but eventually both have similar remineralizing potential.http://www.drjjournal.net/article.asp?issn=1735-3327;year=2016;volume=13;issue=4;spage=297;epage=302;aulast=PalaniswamyCasein phosphopeptide-amorphous calcium phosphate nanocomplexNovaMinenamelremineralizationhardnessnumber
spellingShingle Udaya Kumar Palaniswamy
Neha Prashar
Mamta Kaushik
Surender Ram Lakkam
Shikha Arya
Swetha Pebbeti
A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
Dental Research Journal
Casein phosphopeptide-amorphous calcium phosphate nanocomplex
NovaMin
enamel
remineralization
hardness
number
title A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
title_full A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
title_fullStr A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
title_full_unstemmed A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
title_short A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
title_sort comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion
topic Casein phosphopeptide-amorphous calcium phosphate nanocomplex
NovaMin
enamel
remineralization
hardness
number
url http://www.drjjournal.net/article.asp?issn=1735-3327;year=2016;volume=13;issue=4;spage=297;epage=302;aulast=Palaniswamy
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