Colorimetric miRNA detection based on self-primer-initiated CRISPR-Cas12a-assisted amplification

miRNAs alter significantly throughout pregnancy to support the development of the fetus. However, sensitive detection of miRNA remains a challenge. Herein, a reliable miRNA detection approach integrating self-assembly-triggered signal amplification and CRISPR-Cas12a-system cleavage-based color gener...

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Bibliographic Details
Main Authors: Ying Kang, Jingjing Zhang, Lijuan Zhao, Hongli Yan
Format: Article
Language:English
Published: Future Science Ltd 2023-04-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2023-0008