Pharmacokinetics of Dantrolene in the Plasma Exchange Treatment of Malignant Hyperthermia in a 14-Year-Old Chinese Boy: A Case Report and Literature Review

Pharmacokinetics of Dantrolene in the Plasma Exchange Treatment of Malignant Hyperthermia in a 14-Year-Old Chinese Boy: A Case Report and Literature Review

Malignant hyperthermia (MH) is a rare life-threatening response that is triggered by exposure to specific anesthetics commonly used during surgical interventions. Dantrolene is a well-known drug used as the first-line therapy for MH. A 14-year-old Chinese boy with a mutation in type 1 Ryanodine rece...

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Bibliographic Details
Main Authors: Xiaoxiao Li, Chao Li, Yang Zhou, Zhengqian Li, Xin Xiong, Chuhui Wang, Congya Zhou, Bin Han, Li Yang, Xiangyang Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
malignant hyperthermia
dantrolene
pharmacokinetics
plasma exchange
general anesthesia
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.918245/full

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