Advances in Immunotherapy and the TGF-β Resistance Pathway in Metastatic Bladder Cancer
Bladder cancer accounts for nearly 200,000 deaths worldwide yearly. Urothelial carcinoma (UC) accounts for nearly 90% of cases of bladder cancer. Cisplatin-based chemotherapy has remained the mainstay of treatment in the first-line setting for locally advanced or metastatic UC. More recently, the tr...
Main Authors: | David J. Benjamin, Yung Lyou |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/22/5724 |
Similar Items
-
Activation of the DDR Pathway Leads to the Down-Regulation of the TGFβ Pathway and a Better Response to ICIs in Patients With Metastatic Urothelial Carcinoma
by: Chaozheng Zhou, et al.
Published: (2021-06-01) -
Prognostic Impact of Canonical TGF-β Signaling in Urothelial Bladder Cancer
by: Slavica Stojnev, et al.
Published: (2019-06-01) -
Quantification of the TGF- β/SMAD fibrosis pathway in bladder wall samples from children with congenital lower urinary tract anomalies
by: B. Xie, et al.
Published: (2023-03-01) -
A risk score model based on TGF-β pathway-related genes predicts survival, tumor microenvironment and immunotherapy for liver hepatocellular carcinoma
by: Jingsheng Liao, et al.
Published: (2022-06-01) -
TGF-β in T Cell Biology: Implications for Cancer Immunotherapy
by: Amina Dahmani, et al.
Published: (2018-06-01)