Broad-spectrum antibiotic prophylaxis in tumor and infected orthopedic surgery—the prospective-randomized, microbiologist-blinded, stratified, superiority trials: BAPTIST Trials

Broad-spectrum antibiotic prophylaxis in tumor and infected orthopedic surgery—the prospective-randomized, microbiologist-blinded, stratified, superiority trials: BAPTIST Trials

Abstract Background The perioperative antibiotic prophylaxis with 1st or 2nd generation cephalosporins is evidence-based in orthopedic surgery. There are, however, situations with a high risk of prophylaxis-resistant surgical site infections (SSI). Methods We perform a superiority randomized control...

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Bibliographic Details
Main Authors: Ilker Uçkay, Hagen Bomberg, Markus Risch, Daniel Müller, Michael Betz, Mazda Farshad
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Trials
Subjects:
Orthopedic surgery
Broad-spectrum antibiotic prophylaxis
Surgical site infections
Postoperative healthcare-associated infections
Randomized-controlled trial
Online Access:https://doi.org/10.1186/s13063-023-07605-5

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