Imaging of brown tumours: a pictorial review

Abstract Brown tumours do not represent neoplastic process, but they are focal bony lesions due to bone remodelling from either primary or secondary hyperparathyroidism. Their incidence is also low. The current literature on brown tumour is mainly in the form of case reports that focus on single aff...

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Main Authors: Cheng Xie, Maria Tsakok, Nia Taylor, Karen Partington
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:Insights into Imaging
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13244-019-0757-z
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author Cheng Xie
Maria Tsakok
Nia Taylor
Karen Partington
author_facet Cheng Xie
Maria Tsakok
Nia Taylor
Karen Partington
author_sort Cheng Xie
collection DOAJ
description Abstract Brown tumours do not represent neoplastic process, but they are focal bony lesions due to bone remodelling from either primary or secondary hyperparathyroidism. Their incidence is also low. The current literature on brown tumour is mainly in the form of case reports that focus on single affected sites. This pictorial review describes the full imaging workup and pathway of suspected brown tumour in the setting of both primary and secondary hyperparathyroidism. It aims to illustrate the management strategy to aid both clinicians and radiologists in suspected cases of brown tumour. We highlight the complementary roles that different imaging modalities can play in different settings including the importance of parathyroid ultrasound, 99mTc-sestamibi scintigraphy and SPECT/CT in the localisation of the parathyroid adenoma. We present cases with full clinical and imaging workup in both the acute and chronic setting and scenarios that require exclusion of primary and secondary bone malignancies.
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spelling doaj.art-2665478f8be24e638d9698097ea46f232022-12-21T18:51:20ZengSpringerOpenInsights into Imaging1869-41012019-07-011011910.1186/s13244-019-0757-zImaging of brown tumours: a pictorial reviewCheng Xie0Maria Tsakok1Nia Taylor2Karen Partington3Department of Radiology, John Radcliffe Hospital, Oxford University Hospital TrustDepartment of Radiology, John Radcliffe Hospital, Oxford University Hospital TrustDepartment of Radiology, Churchill Hospital, Oxford University Hospital TrustDepartment of Radiology, Nuffield Orthopaedic Centre, Oxford University Hospital Foundation TrustAbstract Brown tumours do not represent neoplastic process, but they are focal bony lesions due to bone remodelling from either primary or secondary hyperparathyroidism. Their incidence is also low. The current literature on brown tumour is mainly in the form of case reports that focus on single affected sites. This pictorial review describes the full imaging workup and pathway of suspected brown tumour in the setting of both primary and secondary hyperparathyroidism. It aims to illustrate the management strategy to aid both clinicians and radiologists in suspected cases of brown tumour. We highlight the complementary roles that different imaging modalities can play in different settings including the importance of parathyroid ultrasound, 99mTc-sestamibi scintigraphy and SPECT/CT in the localisation of the parathyroid adenoma. We present cases with full clinical and imaging workup in both the acute and chronic setting and scenarios that require exclusion of primary and secondary bone malignancies.http://link.springer.com/article/10.1186/s13244-019-0757-zBrown tumourParathyroid adenomaHyperparathyroidismParathyroid ultrasoundSestamibi
spellingShingle Cheng Xie
Maria Tsakok
Nia Taylor
Karen Partington
Imaging of brown tumours: a pictorial review
Insights into Imaging
Brown tumour
Parathyroid adenoma
Hyperparathyroidism
Parathyroid ultrasound
Sestamibi
title Imaging of brown tumours: a pictorial review
title_full Imaging of brown tumours: a pictorial review
title_fullStr Imaging of brown tumours: a pictorial review
title_full_unstemmed Imaging of brown tumours: a pictorial review
title_short Imaging of brown tumours: a pictorial review
title_sort imaging of brown tumours a pictorial review
topic Brown tumour
Parathyroid adenoma
Hyperparathyroidism
Parathyroid ultrasound
Sestamibi
url http://link.springer.com/article/10.1186/s13244-019-0757-z
work_keys_str_mv AT chengxie imagingofbrowntumoursapictorialreview
AT mariatsakok imagingofbrowntumoursapictorialreview
AT niataylor imagingofbrowntumoursapictorialreview
AT karenpartington imagingofbrowntumoursapictorialreview