Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine
A hydrogel is a three-dimensional structure that holds plenty of water, but brittleness largely limits its application. Self-healing hydrogels, a new type of hydrogel that can be repaired by itself after external damage, have exhibited better fatigue resistance, reusability, hydrophilicity, and resp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/16/3/1215 |
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| author | Wei Zhu Jinyi Zhang Zhanqi Wei Baozhong Zhang Xisheng Weng |
| author_facet | Wei Zhu Jinyi Zhang Zhanqi Wei Baozhong Zhang Xisheng Weng |
| author_sort | Wei Zhu |
| collection | DOAJ |
| description | A hydrogel is a three-dimensional structure that holds plenty of water, but brittleness largely limits its application. Self-healing hydrogels, a new type of hydrogel that can be repaired by itself after external damage, have exhibited better fatigue resistance, reusability, hydrophilicity, and responsiveness to environmental stimuli. The past decade has seen rapid progress in self-healing hydrogels. Self-healing hydrogels can automatically self-repair after external damage. Different strategies have been proposed, including dynamic covalent bonds and reversible noncovalent interactions. Compared to traditional hydrogels, self-healing gels have better durability, responsiveness, and plasticity. These features allow the hydrogel to survive in harsh environments or even to be injected as a drug carrier. Here, we summarize the common strategies for designing self-healing hydrogels and their potential applications in clinical practice. |
| first_indexed | 2024-03-11T09:35:17Z |
| format | Article |
| id | doaj.art-2667e72f869f4a4bb48626527553cc0c |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-11T09:35:17Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-2667e72f869f4a4bb48626527553cc0c2023-11-16T17:18:52ZengMDPI AGMaterials1996-19442023-01-01163121510.3390/ma16031215Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative MedicineWei Zhu0Jinyi Zhang1Zhanqi Wei2Baozhong Zhang3Xisheng Weng4Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaSchool of Medicine, Tsinghua University, Beijing 100084, ChinaSchool of Medicine, Tsinghua University, Beijing 100084, ChinaDepartment of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaA hydrogel is a three-dimensional structure that holds plenty of water, but brittleness largely limits its application. Self-healing hydrogels, a new type of hydrogel that can be repaired by itself after external damage, have exhibited better fatigue resistance, reusability, hydrophilicity, and responsiveness to environmental stimuli. The past decade has seen rapid progress in self-healing hydrogels. Self-healing hydrogels can automatically self-repair after external damage. Different strategies have been proposed, including dynamic covalent bonds and reversible noncovalent interactions. Compared to traditional hydrogels, self-healing gels have better durability, responsiveness, and plasticity. These features allow the hydrogel to survive in harsh environments or even to be injected as a drug carrier. Here, we summarize the common strategies for designing self-healing hydrogels and their potential applications in clinical practice.https://www.mdpi.com/1996-1944/16/3/1215self-healing hydrogelsregenerative medicinebiomaterials |
| spellingShingle | Wei Zhu Jinyi Zhang Zhanqi Wei Baozhong Zhang Xisheng Weng Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine Materials self-healing hydrogels regenerative medicine biomaterials |
| title | Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine |
| title_full | Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine |
| title_fullStr | Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine |
| title_full_unstemmed | Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine |
| title_short | Advances and Progress in Self-Healing Hydrogel and Its Application in Regenerative Medicine |
| title_sort | advances and progress in self healing hydrogel and its application in regenerative medicine |
| topic | self-healing hydrogels regenerative medicine biomaterials |
| url | https://www.mdpi.com/1996-1944/16/3/1215 |
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