Patterns of DNMT1 Promoter Methylation in Patients with Acute Lymphoblastic Leukemia

Patterns of DNMT1 Promoter Methylation in Patients with Acute Lymphoblastic Leukemia

Background: Acute lymphoblastic leukemia (ALL) is a clonal malignant disorder characterized by an uncontrolled proliferation of immature T or B lymphocytes. Extensive studies have shown that the epigenetic changes, especially modified DNA methylation patterns in the regulatory regions through the DN...

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Bibliographic Details
Main Authors: Tirdad Rahmani, Mehdi Azad, Bahram Chahardouli, Hajar Nasiri, Mousa Vatanmakanian, Saeid Kaviani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-12-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Acute lymphocytic leukemia
Epigenetic
Methylation
DNA methyltransferase
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/675

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