Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery
Objective: The aim of study was to demonstrate that transcutaneous intralesional injection of Triamcinolone Acetonide (TA) under fibrolaryngoscopy could be an option for persistent granulation after Transoral Laser Microsurgery (TLM) in glottic cancer patients. Methods: We recruited 32 patients, who...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-05-01
|
| Series: | Brazilian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S180886942300006X |
| _version_ | 1827943645237477376 |
|---|---|
| author | Ying Zhang Shisheng Li |
| author_facet | Ying Zhang Shisheng Li |
| author_sort | Ying Zhang |
| collection | DOAJ |
| description | Objective: The aim of study was to demonstrate that transcutaneous intralesional injection of Triamcinolone Acetonide (TA) under fibrolaryngoscopy could be an option for persistent granulation after Transoral Laser Microsurgery (TLM) in glottic cancer patients. Methods: We recruited 32 patients, who had conservative treatment but failed. 20 patients accepted TA injection monthly until the granulation disappeared or did not shrink further. 12 patients chose to closely monitor. Results: For the 20 patients, 17 (85.0%) patients’ granulations completely disappeared. 3 (15.0%) patients’ granulations had reduced 80%. For the 12 patients, 3 (25.0%) patients’ granulations disappeared but 9 (75%) patients’ granulations did not have an obvious change. Recurrence was not observed. Conclusion: Our experience showed that transcutaneous intralesional TA injection for persistent granulation after TLM through cricothyroid membrane is an efficient, security, harmless and low recurrence method. Especially suitable for huge granulation which blocks the glottis and recur after a second operation. |
| first_indexed | 2024-03-13T10:18:31Z |
| format | Article |
| id | doaj.art-266ccb1230d74487bbd4b827c8635fb3 |
| institution | Directory Open Access Journal |
| issn | 1808-8694 |
| language | English |
| last_indexed | 2024-03-13T10:18:31Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Otorhinolaryngology |
| spelling | doaj.art-266ccb1230d74487bbd4b827c8635fb32023-05-21T04:34:44ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86942023-05-01893359365Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgeryYing Zhang0Shisheng Li1Central South University, The Second Xiangya Hospital, Department of Otolaryngology, Head and Neck Surgery, Hunan, ChinaCorresponding author.; Central South University, The Second Xiangya Hospital, Department of Otolaryngology, Head and Neck Surgery, Hunan, ChinaObjective: The aim of study was to demonstrate that transcutaneous intralesional injection of Triamcinolone Acetonide (TA) under fibrolaryngoscopy could be an option for persistent granulation after Transoral Laser Microsurgery (TLM) in glottic cancer patients. Methods: We recruited 32 patients, who had conservative treatment but failed. 20 patients accepted TA injection monthly until the granulation disappeared or did not shrink further. 12 patients chose to closely monitor. Results: For the 20 patients, 17 (85.0%) patients’ granulations completely disappeared. 3 (15.0%) patients’ granulations had reduced 80%. For the 12 patients, 3 (25.0%) patients’ granulations disappeared but 9 (75%) patients’ granulations did not have an obvious change. Recurrence was not observed. Conclusion: Our experience showed that transcutaneous intralesional TA injection for persistent granulation after TLM through cricothyroid membrane is an efficient, security, harmless and low recurrence method. Especially suitable for huge granulation which blocks the glottis and recur after a second operation.http://www.sciencedirect.com/science/article/pii/S180886942300006XEarly glottic cancer, transoral laser microsurgeryFibrolaryngoscopyPersistent granulomaTriamcinolone acetonideTranscutaneous intralesional injection |
| spellingShingle | Ying Zhang Shisheng Li Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery Brazilian Journal of Otorhinolaryngology Early glottic cancer, transoral laser microsurgery Fibrolaryngoscopy Persistent granuloma Triamcinolone acetonide Transcutaneous intralesional injection |
| title | Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| title_full | Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| title_fullStr | Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| title_full_unstemmed | Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| title_short | Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| title_sort | transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery |
| topic | Early glottic cancer, transoral laser microsurgery Fibrolaryngoscopy Persistent granuloma Triamcinolone acetonide Transcutaneous intralesional injection |
| url | http://www.sciencedirect.com/science/article/pii/S180886942300006X |
| work_keys_str_mv | AT yingzhang transcutaneousinjectionoftriamcinoloneacetonideforpersistentglotticgranulationafterlasermicrosurgery AT shishengli transcutaneousinjectionoftriamcinoloneacetonideforpersistentglotticgranulationafterlasermicrosurgery |