Flavivirus Infection Associated with Cerebrovascular Events
Arthropod-borne viruses (arboviruses) of the genus <i>Flavivirus</i> are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hem...
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MDPI AG
2020-06-01
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Series: | Viruses |
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Online Access: | https://www.mdpi.com/1999-4915/12/6/671 |
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author | Cássia F. Estofolete Bruno H. G. A. Milhim Nathalia Zini Samuel N. Scamardi Joana D’Arc Selvante Nikos Vasilakis Maurício L. Nogueira |
author_facet | Cássia F. Estofolete Bruno H. G. A. Milhim Nathalia Zini Samuel N. Scamardi Joana D’Arc Selvante Nikos Vasilakis Maurício L. Nogueira |
author_sort | Cássia F. Estofolete |
collection | DOAJ |
description | Arthropod-borne viruses (arboviruses) of the genus <i>Flavivirus</i> are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hemorrhage, encephalitis and death. Herein, we describe 3 case reports of cerebrovascular involvement in patients infected by dengue and Zika viruses in Sao Jose do Rio Preto, São Paulo State, Brazil, a hyperendemic area for arbovirus circulation, including dengue, yellow fever, chikungunya and Saint Louis encephalitis viruses. Our findings highlight the potential threat that unusual clinical manifestations may pose to arbovirus disease management and recovery. |
first_indexed | 2024-03-10T18:58:02Z |
format | Article |
id | doaj.art-26725178061d430fb7bb297bcac9d1a8 |
institution | Directory Open Access Journal |
issn | 1999-4915 |
language | English |
last_indexed | 2024-03-10T18:58:02Z |
publishDate | 2020-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Viruses |
spelling | doaj.art-26725178061d430fb7bb297bcac9d1a82023-11-20T04:35:34ZengMDPI AGViruses1999-49152020-06-0112667110.3390/v12060671Flavivirus Infection Associated with Cerebrovascular EventsCássia F. Estofolete0Bruno H. G. A. Milhim1Nathalia Zini2Samuel N. Scamardi3Joana D’Arc Selvante4Nikos Vasilakis5Maurício L. Nogueira6Department of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilDepartment of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilDepartment of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilDepartment of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilDepartment of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilDepartment of Pathology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0609, USADepartment of Infectious, Dermatological and Parasitic Infections, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto 15090-000, BrazilArthropod-borne viruses (arboviruses) of the genus <i>Flavivirus</i> are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hemorrhage, encephalitis and death. Herein, we describe 3 case reports of cerebrovascular involvement in patients infected by dengue and Zika viruses in Sao Jose do Rio Preto, São Paulo State, Brazil, a hyperendemic area for arbovirus circulation, including dengue, yellow fever, chikungunya and Saint Louis encephalitis viruses. Our findings highlight the potential threat that unusual clinical manifestations may pose to arbovirus disease management and recovery.https://www.mdpi.com/1999-4915/12/6/671Zika virusdengue virusatypical manifestationscerebrovascular events |
spellingShingle | Cássia F. Estofolete Bruno H. G. A. Milhim Nathalia Zini Samuel N. Scamardi Joana D’Arc Selvante Nikos Vasilakis Maurício L. Nogueira Flavivirus Infection Associated with Cerebrovascular Events Viruses Zika virus dengue virus atypical manifestations cerebrovascular events |
title | Flavivirus Infection Associated with Cerebrovascular Events |
title_full | Flavivirus Infection Associated with Cerebrovascular Events |
title_fullStr | Flavivirus Infection Associated with Cerebrovascular Events |
title_full_unstemmed | Flavivirus Infection Associated with Cerebrovascular Events |
title_short | Flavivirus Infection Associated with Cerebrovascular Events |
title_sort | flavivirus infection associated with cerebrovascular events |
topic | Zika virus dengue virus atypical manifestations cerebrovascular events |
url | https://www.mdpi.com/1999-4915/12/6/671 |
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