Recent advances in LDH-based nanosystems for cancer therapy
Cancer has become one of the greatest causes of death around the world. The treatment of cancer still remains a great problem. With recent advances made in the field of nanotechnology, layered double hydroxide (LDH)-based nanosystems have drawn special attention because of their good biocompatibilit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127520308340 |
| _version_ | 1818564483869573120 |
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| author | Jia Wen Kui Yang Jie Huang Shiguo Sun |
| author_facet | Jia Wen Kui Yang Jie Huang Shiguo Sun |
| author_sort | Jia Wen |
| collection | DOAJ |
| description | Cancer has become one of the greatest causes of death around the world. The treatment of cancer still remains a great problem. With recent advances made in the field of nanotechnology, layered double hydroxide (LDH)-based nanosystems have drawn special attention because of their good biocompatibility, pH-dependent biodegradability, anion exchange capacity, easy surface modification and high chemical stability, giving rise to great potential for cancer therapy. In the past decade, LDH-based nanosystems have been constructed for various cancer therapies. However, few review articles have described these important and promising achievements to promote the further development of LDH and its nanocomposites. This review aims to provide a comprehensive overview on the recent developments in LDH and its nanocomposites as powerful nanosystems for diverse cancer therapies, which is divided into five parts: chemotherapy, phototherapy, gene therapy, immunotherapy and combination therapy. This review also outlines future perspectives and current challenges in LDH and its nanocomposites for cancer therapy. |
| first_indexed | 2024-12-14T01:29:32Z |
| format | Article |
| id | doaj.art-267275f30caa44aa8bf4b5dc5c813196 |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-12-14T01:29:32Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-267275f30caa44aa8bf4b5dc5c8131962022-12-21T23:22:04ZengElsevierMaterials & Design0264-12752021-01-01198109298Recent advances in LDH-based nanosystems for cancer therapyJia Wen0Kui Yang1Jie Huang2Shiguo Sun3Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, ChinaLaboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, ChinaKey Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, ChinaCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, Hebei 050018, China; Corresponding author.Cancer has become one of the greatest causes of death around the world. The treatment of cancer still remains a great problem. With recent advances made in the field of nanotechnology, layered double hydroxide (LDH)-based nanosystems have drawn special attention because of their good biocompatibility, pH-dependent biodegradability, anion exchange capacity, easy surface modification and high chemical stability, giving rise to great potential for cancer therapy. In the past decade, LDH-based nanosystems have been constructed for various cancer therapies. However, few review articles have described these important and promising achievements to promote the further development of LDH and its nanocomposites. This review aims to provide a comprehensive overview on the recent developments in LDH and its nanocomposites as powerful nanosystems for diverse cancer therapies, which is divided into five parts: chemotherapy, phototherapy, gene therapy, immunotherapy and combination therapy. This review also outlines future perspectives and current challenges in LDH and its nanocomposites for cancer therapy.http://www.sciencedirect.com/science/article/pii/S0264127520308340Layered double hydroxideChemotherapyPhototherapyGene therapyImmunotherapyCombination therapy |
| spellingShingle | Jia Wen Kui Yang Jie Huang Shiguo Sun Recent advances in LDH-based nanosystems for cancer therapy Materials & Design Layered double hydroxide Chemotherapy Phototherapy Gene therapy Immunotherapy Combination therapy |
| title | Recent advances in LDH-based nanosystems for cancer therapy |
| title_full | Recent advances in LDH-based nanosystems for cancer therapy |
| title_fullStr | Recent advances in LDH-based nanosystems for cancer therapy |
| title_full_unstemmed | Recent advances in LDH-based nanosystems for cancer therapy |
| title_short | Recent advances in LDH-based nanosystems for cancer therapy |
| title_sort | recent advances in ldh based nanosystems for cancer therapy |
| topic | Layered double hydroxide Chemotherapy Phototherapy Gene therapy Immunotherapy Combination therapy |
| url | http://www.sciencedirect.com/science/article/pii/S0264127520308340 |
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