Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography
ObjectiveThe objective of this study was to analyze the changes in connectivity between motor imagery (MI) and motor execution (ME) in the premotor area (PMA) and primary motor cortex (MA) of the brain, aiming to explore suitable forms of treatment and potential therapeutic targets.MethodsTwenty-thr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2024.1330280/full |
| _version_ | 1797334783117754368 |
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| author | Dongju Guo Jinglu Hu Dezheng Wang Chongfeng Wang Shouwei Yue Fangzhou Xu Yang Zhang Yang Zhang |
| author_facet | Dongju Guo Jinglu Hu Dezheng Wang Chongfeng Wang Shouwei Yue Fangzhou Xu Yang Zhang Yang Zhang |
| author_sort | Dongju Guo |
| collection | DOAJ |
| description | ObjectiveThe objective of this study was to analyze the changes in connectivity between motor imagery (MI) and motor execution (ME) in the premotor area (PMA) and primary motor cortex (MA) of the brain, aiming to explore suitable forms of treatment and potential therapeutic targets.MethodsTwenty-three inpatients with stroke were selected, and 21 right-handed healthy individuals were recruited. EEG signal during hand MI and ME (synergy and isolated movements) was recorded. Correlations between functional brain areas during MI and ME were compared.ResultsPMA and MA were significantly and positively correlated during hand MI in all participants. The power spectral density (PSD) values of PMA EEG signals were greater than those of MA during MI and ME in both groups. The functional connectivity correlation was higher in the stroke group than in healthy people during MI, especially during left-handed MI. During ME, functional connectivity correlation in the brain was more enhanced during synergy movements than during isolated movements. The regions with abnormal functional connectivity were in the 18th lead of the left PMA area.ConclusionLeft-handed MI may be crucial in MI therapy, and the 18th lead may serve as a target for non-invasive neuromodulation to promote further recovery of limb function in patients with stroke. This may provide support for the EEG theory of neuromodulation therapy for hemiplegic patients. |
| first_indexed | 2024-03-08T08:26:13Z |
| format | Article |
| id | doaj.art-26750445fbc746a7931682363ef64be4 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-03-08T08:26:13Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-26750445fbc746a7931682363ef64be42024-02-02T04:34:22ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2024-02-011810.3389/fnins.2024.13302801330280Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalographyDongju Guo0Jinglu Hu1Dezheng Wang2Chongfeng Wang3Shouwei Yue4Fangzhou Xu5Yang Zhang6Yang Zhang7Rehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaRehabilitation and Physical Therapy Department, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, ChinaObjectiveThe objective of this study was to analyze the changes in connectivity between motor imagery (MI) and motor execution (ME) in the premotor area (PMA) and primary motor cortex (MA) of the brain, aiming to explore suitable forms of treatment and potential therapeutic targets.MethodsTwenty-three inpatients with stroke were selected, and 21 right-handed healthy individuals were recruited. EEG signal during hand MI and ME (synergy and isolated movements) was recorded. Correlations between functional brain areas during MI and ME were compared.ResultsPMA and MA were significantly and positively correlated during hand MI in all participants. The power spectral density (PSD) values of PMA EEG signals were greater than those of MA during MI and ME in both groups. The functional connectivity correlation was higher in the stroke group than in healthy people during MI, especially during left-handed MI. During ME, functional connectivity correlation in the brain was more enhanced during synergy movements than during isolated movements. The regions with abnormal functional connectivity were in the 18th lead of the left PMA area.ConclusionLeft-handed MI may be crucial in MI therapy, and the 18th lead may serve as a target for non-invasive neuromodulation to promote further recovery of limb function in patients with stroke. This may provide support for the EEG theory of neuromodulation therapy for hemiplegic patients.https://www.frontiersin.org/articles/10.3389/fnins.2024.1330280/fullmotor imagerystrokeelectroencephalographymotor executionpremotor areaprimary motor cortex |
| spellingShingle | Dongju Guo Jinglu Hu Dezheng Wang Chongfeng Wang Shouwei Yue Fangzhou Xu Yang Zhang Yang Zhang Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography Frontiers in Neuroscience motor imagery stroke electroencephalography motor execution premotor area primary motor cortex |
| title | Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| title_full | Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| title_fullStr | Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| title_full_unstemmed | Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| title_short | Variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| title_sort | variation in brain connectivity during motor imagery and motor execution in stroke patients based on electroencephalography |
| topic | motor imagery stroke electroencephalography motor execution premotor area primary motor cortex |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2024.1330280/full |
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