The occurrence and development of induced pluripotent stem cells

The occurrence and development of induced pluripotent stem cells

The ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc (OSKM), known as “Yamanaka factors,” can reprogram or stimulate the production of induced pluripotent stem cells (iPSCs). Although OSKM is still the gold standard, there are multiple ways to reprogram cells into iPSC...

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Bibliographic Details
Main Authors: Yi Chen, Meng Li, Yanqing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Genetics
Subjects:
induced pluripotent stem cells
iPSCs
OSKM
reprogram
epigenetic barriers
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1389558/full

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