Solid-state NMR in the field of drug delivery: State of the art and new perspectives

In the last decades, a variety of nuclear magnetic resonance (NMR) techniques have been applied with success in the field of advanced functional materials, including the important area of drug delivery. In such field, solid-state NMR (SSNMR) is an irreplaceable tool in the arsenal of characterizatio...

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Main Authors: Alessandro Marchetti, Jinglin Yin, Yongchao Su, Xueqian Kong
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2021-08-01
Series:Magnetic Resonance Letters
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772516221000036
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author Alessandro Marchetti
Jinglin Yin
Yongchao Su
Xueqian Kong
author_facet Alessandro Marchetti
Jinglin Yin
Yongchao Su
Xueqian Kong
author_sort Alessandro Marchetti
collection DOAJ
description In the last decades, a variety of nuclear magnetic resonance (NMR) techniques have been applied with success in the field of advanced functional materials, including the important area of drug delivery. In such field, solid-state NMR (SSNMR) is an irreplaceable tool in the arsenal of characterization techniques, offering unique and comprehensive perspectives for the description of chemical structure, spatial connectivity and interfacial phenomena of solid dosage forms. This review focuses on the widespread applications of SSNMR in drug delivery field, an overview of selected case studies is provided, together with possible developments.
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spelling doaj.art-267b48cd4e1743139b8c9039d5603d422022-12-22T03:01:57ZengKeAi Communications Co. Ltd.Magnetic Resonance Letters2772-51622021-08-01112870Solid-state NMR in the field of drug delivery: State of the art and new perspectivesAlessandro Marchetti0Jinglin Yin1Yongchao Su2Xueqian Kong3Department of Rehabilitation, Sir Run Run Shaw Hospital, School of Medicine, & Department of Chemistry, Zhejiang University, Hangzhou, 310027, ChinaDepartment of Rehabilitation, Sir Run Run Shaw Hospital, School of Medicine, & Department of Chemistry, Zhejiang University, Hangzhou, 310027, ChinaDivision of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA; Corresponding authors.Department of Rehabilitation, Sir Run Run Shaw Hospital, School of Medicine, & Department of Chemistry, Zhejiang University, Hangzhou, 310027, China; Corresponding authors.In the last decades, a variety of nuclear magnetic resonance (NMR) techniques have been applied with success in the field of advanced functional materials, including the important area of drug delivery. In such field, solid-state NMR (SSNMR) is an irreplaceable tool in the arsenal of characterization techniques, offering unique and comprehensive perspectives for the description of chemical structure, spatial connectivity and interfacial phenomena of solid dosage forms. This review focuses on the widespread applications of SSNMR in drug delivery field, an overview of selected case studies is provided, together with possible developments.http://www.sciencedirect.com/science/article/pii/S2772516221000036Solid-state NMRDrug deliveryDrug-polymer interactionPharmaceuticsDrug formulation
spellingShingle Alessandro Marchetti
Jinglin Yin
Yongchao Su
Xueqian Kong
Solid-state NMR in the field of drug delivery: State of the art and new perspectives
Magnetic Resonance Letters
Solid-state NMR
Drug delivery
Drug-polymer interaction
Pharmaceutics
Drug formulation
title Solid-state NMR in the field of drug delivery: State of the art and new perspectives
title_full Solid-state NMR in the field of drug delivery: State of the art and new perspectives
title_fullStr Solid-state NMR in the field of drug delivery: State of the art and new perspectives
title_full_unstemmed Solid-state NMR in the field of drug delivery: State of the art and new perspectives
title_short Solid-state NMR in the field of drug delivery: State of the art and new perspectives
title_sort solid state nmr in the field of drug delivery state of the art and new perspectives
topic Solid-state NMR
Drug delivery
Drug-polymer interaction
Pharmaceutics
Drug formulation
url http://www.sciencedirect.com/science/article/pii/S2772516221000036
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AT xueqiankong solidstatenmrinthefieldofdrugdeliverystateoftheartandnewperspectives