Interferon Status and Choice of Interferons Inducers in Frequently Ill Children

Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has only failure of interferon system, and 34% of...

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Main Authors: M. S. Savenkovа, O. V. Karashtinа, M. B. Shabat, G. N. Kraseva, N. A. Abramova, T. E. Kraseva
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2016-06-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/227
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author M. S. Savenkovа
O. V. Karashtinа
M. B. Shabat
G. N. Kraseva
N. A. Abramova
T. E. Kraseva
author_facet M. S. Savenkovа
O. V. Karashtinа
M. B. Shabat
G. N. Kraseva
N. A. Abramova
T. E. Kraseva
author_sort M. S. Savenkovа
collection DOAJ
description Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has only failure of interferon system, and 34% of FIC has violations of humoral immunity in combination with interferon system failure. At the same time, all children suffering occasionally was detected only insufficiency of interferon system and humoral immunity was within normal limits. Based on the study of individual sensitivity of white blood cells justifies the choice of interferons inducers.
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spelling doaj.art-267b5002fe97425b8bbf2c4e30defd5a2023-03-13T07:28:23ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072016-06-01152455110.22627/2072-8107-2016-15-2-45-51226Interferon Status and Choice of Interferons Inducers in Frequently Ill ChildrenM. S. Savenkovа0O. V. Karashtinа1M. B. Shabat2G. N. Kraseva3N. A. Abramova4T. E. Kraseva5Российский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ, МоскваLiterature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has only failure of interferon system, and 34% of FIC has violations of humoral immunity in combination with interferon system failure. At the same time, all children suffering occasionally was detected only insufficiency of interferon system and humoral immunity was within normal limits. Based on the study of individual sensitivity of white blood cells justifies the choice of interferons inducers.https://detinf.elpub.ru/jour/article/view/227интерфероновый статусальфа-ифнгамма-ифниндукторы интерфероновдети
spellingShingle M. S. Savenkovа
O. V. Karashtinа
M. B. Shabat
G. N. Kraseva
N. A. Abramova
T. E. Kraseva
Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
Детские инфекции (Москва)
интерфероновый статус
альфа-ифн
гамма-ифн
индукторы интерферонов
дети
title Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
title_full Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
title_fullStr Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
title_full_unstemmed Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
title_short Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
title_sort interferon status and choice of interferons inducers in frequently ill children
topic интерфероновый статус
альфа-ифн
гамма-ифн
индукторы интерферонов
дети
url https://detinf.elpub.ru/jour/article/view/227
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