ATP and nucleic acids competitively modulate LLPS of the SARS-CoV2 nucleocapsid protein
An NMR-centered approach demonstrates that the liquid-liquid phase separation behavior of the SARS-CoV-2 nucleocapsid (N) protein is modulated by competitive interactions with ATP and nucleic acids.
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04480-3 |