IL-27 Regulates IL-18 binding protein in skin resident cells.
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased IL-18 activity. IL-27 is a cytokine with dual...
Main Authors: | Miriam Wittmann, Rosella Doble, Malte Bachmann, Josef Pfeilschifter, Thomas Werfel, Heiko Mühl |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3384590?pdf=render |
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