Perinatal MAO Inhibition Produces Long-Lasting Impairment of Serotonin Function in Offspring

Perinatal MAO Inhibition Produces Long-Lasting Impairment of Serotonin Function in Offspring

In addition to transmitter functions, many neuroamines have trophic or ontogenetic regulatory effects important to both normal and disordered brain development. In previous work (Mejia et al., 2002), we showed that pharmacologically inhibiting monoamine oxidase (MAO) activity during murine gestation...

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Bibliographic Details
Main Authors: Mark W. Burke, Myriam Fillion, Jose Mejia, Frank R. Ervin, Roberta M. Palmour
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Brain Sciences
Subjects:
serotonin transporter
dopamine transporter
neurodevelopment
MAO inhibition
aggression
anxiety
Online Access:http://www.mdpi.com/2076-3425/8/6/106

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