HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region

HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region

Hexavalent chromium [Cr (VI)] exists environmentally and occupationally. It has been shown to pose a carcinogenic hazard in certain occupations. This study was to investigate the role of high mobility group A2 (HMGA2) in Cr (VI)-induced metabolism reprogramming from oxidative phosphorylation (OXPHOS...

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Bibliographic Details
Main Authors: Shibo Bao, Cong Zhang, Shengxiang Luo, Liping Jiang, Qiujuan Li, Ying Kong, Jun Cao
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Potassium dichromate
HMGA2
Glycolysis
Oxidative phosphorylation
ER stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322009253

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