Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study
Vaccine booster dose (VBD) provides a potential therapeutic alliance in preventing breakthrough infection and new variant's arrival while preserving long-lasting host immunity. This study aimed to analyze COVID-19 VBD willingness and identified the key determinants of VBD acceptance among the g...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023094239 |
| _version_ | 1797429677050036224 |
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| author | Debendra Nath Roy Shaheb Ali Ashish Kumar Sarker Ekramul Islam Md. Shah Azam |
| author_facet | Debendra Nath Roy Shaheb Ali Ashish Kumar Sarker Ekramul Islam Md. Shah Azam |
| author_sort | Debendra Nath Roy |
| collection | DOAJ |
| description | Vaccine booster dose (VBD) provides a potential therapeutic alliance in preventing breakthrough infection and new variant's arrival while preserving long-lasting host immunity. This study aimed to analyze COVID-19 VBD willingness and identified the key determinants of VBD acceptance among the general people of Bangladesh. This survey-based study applied a quantitative research paradigm. A validated, anonymous, and multi-item questionnaire was adopted through a theoretical review of pertinent literature on the topic. Data were collected between August 2022─October 2022, and sampling was done randomly. A total of 704 individuals were invited via face-to-face interview approach; however, 13.8 % of them declined to give consent, which resulted in the participation of 607 potential respondents. The main outcome measure was COVID-19 VBD acceptance willingness. Binary logistic regression analysis was conducted to rationalize the study's objectives. The pooled COVID-19 booster vaccine acceptance rate was 70.0 % (95 % confidence Interval [CI]: 67─73) among Bangladeshi people. An analysis of binary logistic regression revealed that, out of 14 potential factors, “efficacy”, “repeated immunity”, ”communication”, and “trust” showed highly significant positive association (adjusted odds ratio [aOR ] = 2.151 95 % CI: 1.391─ 3.508, aOR = 2.033 95 % CI: 1.299─ 3.181, and aOR = 2.552 95 % CI: 1.557─4.183 respectively, p<0.01), and “equal safety”, “risk-benefit ratio” and “community protection” had significant positive association (aOR = 1.739 95 % CI: 1.070─2.825, aOR = 1.712 95 % CI: 1.116─2.627, and aOR = 1.628 95 % CI: 1.395─0.998, p<0.05) with VBD acceptance. However, post-vaccination “side effects” showed significant negative (aOR = 0.393 95 % CI: 0.237─0.674, p<0.01) associations with VBD acceptance. The odds of accepting the COVID-19 vaccine booster was found 1.26, and it was found insignificant (p>0.05) in the Chi-squared test. Bangladeshi people expressed a moderately high level response to COVID-19 VBD acceptance. A positive attitude towards the COVID-19 VBD is an outcome of this study, regardless of the circumstances, as far as safety, efficacy, perceived health benefits, communication, trust, and community resistance are concerned. Post-vaccination side effects fear was the primary reason for booster dose skepticism as well as a barrier to administering booster shots. The confidence in COVID-19 VBD will be boosted when mass people are effectively communicated and vaccine's data become more available publicly. |
| first_indexed | 2024-03-09T09:16:36Z |
| format | Article |
| id | doaj.art-268b1e9c11c84d63adb408147dec7890 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-09T09:16:36Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-268b1e9c11c84d63adb408147dec78902023-12-02T07:05:28ZengElsevierHeliyon2405-84402023-11-01911e22215Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional studyDebendra Nath Roy0Shaheb Ali1Ashish Kumar Sarker2Ekramul Islam3Md. Shah Azam4Department of Pharmacy, Jashore University of Science and Technology, Jashore-7408, Bangladesh; Institute of Education and Research, University of Rajshahi, Rajshahi-6205, Bangladesh; Corresponding author.Department of Pharmacy, Jashore University of Science and Technology Jashore-7408, Bangladesh.Department of Pharmacy, Jashore University of Science and Technology, Jashore-7408, BangladeshDepartment of Pharmacy, Pabna University of Science and Technology, Pabna, Bangladesh; School of Science, Western Sydney University, NSW-2560, AustraliaDepartment of Pharmacy, University of Rajshahi, Rajshahi-6205, BangladeshDepartment of Marketing, University of Rajshahi, Rajshahi-6205, Bangladesh; Office of the Vice Chancellor, Rabindra University, Bangladesh; Corresponding author. Department of Marketing, University of Rajshahi, Rajshahi-6205, Bangladesh.Vaccine booster dose (VBD) provides a potential therapeutic alliance in preventing breakthrough infection and new variant's arrival while preserving long-lasting host immunity. This study aimed to analyze COVID-19 VBD willingness and identified the key determinants of VBD acceptance among the general people of Bangladesh. This survey-based study applied a quantitative research paradigm. A validated, anonymous, and multi-item questionnaire was adopted through a theoretical review of pertinent literature on the topic. Data were collected between August 2022─October 2022, and sampling was done randomly. A total of 704 individuals were invited via face-to-face interview approach; however, 13.8 % of them declined to give consent, which resulted in the participation of 607 potential respondents. The main outcome measure was COVID-19 VBD acceptance willingness. Binary logistic regression analysis was conducted to rationalize the study's objectives. The pooled COVID-19 booster vaccine acceptance rate was 70.0 % (95 % confidence Interval [CI]: 67─73) among Bangladeshi people. An analysis of binary logistic regression revealed that, out of 14 potential factors, “efficacy”, “repeated immunity”, ”communication”, and “trust” showed highly significant positive association (adjusted odds ratio [aOR ] = 2.151 95 % CI: 1.391─ 3.508, aOR = 2.033 95 % CI: 1.299─ 3.181, and aOR = 2.552 95 % CI: 1.557─4.183 respectively, p<0.01), and “equal safety”, “risk-benefit ratio” and “community protection” had significant positive association (aOR = 1.739 95 % CI: 1.070─2.825, aOR = 1.712 95 % CI: 1.116─2.627, and aOR = 1.628 95 % CI: 1.395─0.998, p<0.05) with VBD acceptance. However, post-vaccination “side effects” showed significant negative (aOR = 0.393 95 % CI: 0.237─0.674, p<0.01) associations with VBD acceptance. The odds of accepting the COVID-19 vaccine booster was found 1.26, and it was found insignificant (p>0.05) in the Chi-squared test. Bangladeshi people expressed a moderately high level response to COVID-19 VBD acceptance. A positive attitude towards the COVID-19 VBD is an outcome of this study, regardless of the circumstances, as far as safety, efficacy, perceived health benefits, communication, trust, and community resistance are concerned. Post-vaccination side effects fear was the primary reason for booster dose skepticism as well as a barrier to administering booster shots. The confidence in COVID-19 VBD will be boosted when mass people are effectively communicated and vaccine's data become more available publicly.http://www.sciencedirect.com/science/article/pii/S2405844023094239COVID-19Vaccine boosterAcceptancePeopleBangladesh |
| spellingShingle | Debendra Nath Roy Shaheb Ali Ashish Kumar Sarker Ekramul Islam Md. Shah Azam Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study Heliyon COVID-19 Vaccine booster Acceptance People Bangladesh |
| title | Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study |
| title_full | Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study |
| title_fullStr | Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study |
| title_full_unstemmed | Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study |
| title_short | Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study |
| title_sort | acceptance of covid 19 vaccine booster dose among the people of bangladesh a cross sectional study |
| topic | COVID-19 Vaccine booster Acceptance People Bangladesh |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023094239 |
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