How Enzymes Work: A Look through the Perspective of Molecular Viscoelastic Properties
We present nanorheology measurements on the folded state of an enzyme that show directly that the (ensemble-averaged) stress-strain relations are nonlinear and frequency dependent beyond 1-Å deformation. We argue that this frequency dependence allows for opening a nonequilibrium cycle in the force-d...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Physical Society
2013-02-01
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| Series: | Physical Review X |
| Online Access: | http://doi.org/10.1103/PhysRevX.3.011009 |