Homogeneous Synthesis of Cationic Chitosan via New Avenue
Using a solvent formed of alkali and urea, chitosan was successfully dissolved in a new solvent via the freezing–thawing process. Subsequently, quaternized chitosan (QC) was synthesized using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC) as the cationic reagent under different incuba...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/23/8/1921 |
| _version_ | 1818116108383682560 |
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| author | Huanlu Song Hao Wu ShuJing Li Huafeng Tian YanRu Li JianGuo Wang |
| author_facet | Huanlu Song Hao Wu ShuJing Li Huafeng Tian YanRu Li JianGuo Wang |
| author_sort | Huanlu Song |
| collection | DOAJ |
| description | Using a solvent formed of alkali and urea, chitosan was successfully dissolved in a new solvent via the freezing–thawing process. Subsequently, quaternized chitosan (QC) was synthesized using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC) as the cationic reagent under different incubation times and temperatures in a homogeneous system. QCs cannot be synthesized at temperatures above 60 °C, as gel formation will occur. The structure and properties of the prepared QC were characterized and quaternary groups were comfirmed to be successfully incorporated onto chitosan backbones. The degree of substitution (DS) ranged from 16.5% to 46.8% and the yields ranged from 32.6% to 89.7%, which can be adjusted by changing the molar ratio of the chitosan unit to CHPTAC and the reaction time. QCs inhibits the growth of Alicyclobacillus acidoterrestris effectively. Thus, this work offers a simple and green method of functionalizing chitosan and producing quaternized chitosan with an antibacterial effect for potential applications in the food industry. |
| first_indexed | 2024-12-11T04:17:16Z |
| format | Article |
| id | doaj.art-269ae5cbcd0b41099cd1a44e27424354 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-11T04:17:16Z |
| publishDate | 2018-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-269ae5cbcd0b41099cd1a44e274243542022-12-22T01:21:13ZengMDPI AGMolecules1420-30492018-08-01238192110.3390/molecules23081921molecules23081921Homogeneous Synthesis of Cationic Chitosan via New AvenueHuanlu Song0Hao Wu1ShuJing Li2Huafeng Tian3YanRu Li4JianGuo Wang5Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), Beijing 100048, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), Beijing 100048, ChinaBeijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University, Beijing 100048, ChinaBeijing Key Laboratory of Quality Evaluation Technology for Hygiene and Safety of Plastics, Beijing Technology and Business University (BTBU), Beijing 100048, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), Beijing 100048, ChinaUsing a solvent formed of alkali and urea, chitosan was successfully dissolved in a new solvent via the freezing–thawing process. Subsequently, quaternized chitosan (QC) was synthesized using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC) as the cationic reagent under different incubation times and temperatures in a homogeneous system. QCs cannot be synthesized at temperatures above 60 °C, as gel formation will occur. The structure and properties of the prepared QC were characterized and quaternary groups were comfirmed to be successfully incorporated onto chitosan backbones. The degree of substitution (DS) ranged from 16.5% to 46.8% and the yields ranged from 32.6% to 89.7%, which can be adjusted by changing the molar ratio of the chitosan unit to CHPTAC and the reaction time. QCs inhibits the growth of Alicyclobacillus acidoterrestris effectively. Thus, this work offers a simple and green method of functionalizing chitosan and producing quaternized chitosan with an antibacterial effect for potential applications in the food industry.http://www.mdpi.com/1420-3049/23/8/1921chitosanhomogeneous systemquaternizationcharacterizationAlicyclobacillus acidoterrestris |
| spellingShingle | Huanlu Song Hao Wu ShuJing Li Huafeng Tian YanRu Li JianGuo Wang Homogeneous Synthesis of Cationic Chitosan via New Avenue Molecules chitosan homogeneous system quaternization characterization Alicyclobacillus acidoterrestris |
| title | Homogeneous Synthesis of Cationic Chitosan via New Avenue |
| title_full | Homogeneous Synthesis of Cationic Chitosan via New Avenue |
| title_fullStr | Homogeneous Synthesis of Cationic Chitosan via New Avenue |
| title_full_unstemmed | Homogeneous Synthesis of Cationic Chitosan via New Avenue |
| title_short | Homogeneous Synthesis of Cationic Chitosan via New Avenue |
| title_sort | homogeneous synthesis of cationic chitosan via new avenue |
| topic | chitosan homogeneous system quaternization characterization Alicyclobacillus acidoterrestris |
| url | http://www.mdpi.com/1420-3049/23/8/1921 |
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