Anti-β2GPI-domain I antibody is associated with extra-criteria manifestations in a large prospective antiphospholipid syndrome cohort in China

Anti-β2GPI-domain I antibody is associated with extra-criteria manifestations in a large prospective antiphospholipid syndrome cohort in China

Background Anti-β2GPI-domain I (β2GPI-DI) antibody is pathogenic in patients with antiphospholipid syndrome (APS), but its additional clinical associations and diagnostic value are controversial.Methods A total of 378 patients were included, of which 119 patients diagnosed with primary APS, 50 with...

Full description

Bibliographic Details
Main Authors:	Xiaofeng Zeng, Qian Wang, Jiuliang Zhao, Xinping Tian, Mengtao Li, Chaojun Hu, Can Huang, Yangzhong Zhou, Wanting Qi, Yin Long
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-11-01
Series:	Lupus Science and Medicine
Online Access:	https://lupus.bmj.com/content/10/2/e000924.full

Similar Items

Extra-criteria clinical manifestations of antiphospholipid antibody should not be ignored
by: Can Huang, et al.
Published: (2022-09-01)

Prevalence and diagnostic value of non-criteria antiphospholipid antibodies for antiphospholipid syndrome in Chinese patients
by: Siting Li, et al.
Published: (2023-04-01)

Serum Calprotectin as a Potential Predictor of Microvascular Manifestations in Patients with Antiphospholipid Syndrome
by: Yuan Zhao, et al.
Published: (2023-10-01)

Dancing with disorder: chorea – an unusual and neglected manifestation of antiphospholipid syndrome
by: Xiaofeng Zeng, et al.
Published: (2024-10-01)

PO.2.38 Anti-β2GPI-domain 1 antibodies stratify high risk of extra-criteria manifestations in a large prospective chinese cohort of antiphospholipid syndrome
by: Y Zhou, et al.
Published: (2022-10-01)

Immunoglobulin A Isotype of Antiphospholipid Antibodies Does Not Provide Added Value for the Diagnosis of Antiphospholipid Syndrome in a Chinese Population
by: Chaojun Hu, et al.
Published: (2020-10-01)

Validation of three prediction models for thrombosis recurrence in antiphospholipid syndrome patients based on a prospective cohort
by: Xiaofeng Zeng, et al.
Published: (2023-07-01)

Clinical characteristics and prognosis of patients with antiphospholipid antibodies based on cluster analysis: an 8-year cohort study
by: Wanting Qi, et al.
Published: (2022-06-01)

The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome
by: Si Cheng, et al.
Published: (2016-01-01)

Platelet-derived microparticles stimulated by anti-β2GPI/β2GPI complexes induce pyroptosis of endothelial cells in antiphospholipid syndrome
by: Longjiang Di, et al.
Published: (2023-12-01)

Detection of IgA Antiphospholipid Antibodies Does not Improve Thrombotic Antiphospholipid Syndrome Classification: A two-Center Study
by: Zhenzhen Su MM, et al.
Published: (2022-04-01)

LSO-009 The impact of high-risk antiphospholipid antibodies profile on major organ damage progression in systemic lupus erythematosus: CSTAR multiple prospective cohort study
by: Xiaofeng Zeng, et al.
Published: (2023-07-01)

Chronic abdominal aortic occlusive disease related to antiphospholipid syndrome: a rare presentation
by: Wei Liu, et al.
Published: (2024-02-01)

Criteria and Non-Criteria Antiphospholipid Antibodies in Antiphospholipid Syndrome: How Strong Are They Correlated?
by: Simona Caraiola, et al.
Published: (2023-08-01)

Future atherosclerotic cardiovascular disease in systemic lupus erythematosus based on CSTAR (XXVIII): the effect of different antiphospholipid antibodies isotypes
by: Can Huang, et al.
Published: (2025-01-01)

Prevalence of anti- beta2GPI antibodies and their isotypes in patients with renal diseases and clinical suspicion of antiphospholipid syndrome
by: Sabiha Anis, et al.
Published: (2013-07-01)

Sex Differences in Clinical Characteristics and Prognosis in Primary Thrombotic Antiphospholipid Syndrome
by: Yongfa Huang, et al.
Published: (2022-07-01)

Non-criteria antiphospholipid antibodies in antiphospholipid syndrome: Diagnostic value added
by: Xiangjun Liu, et al.
Published: (2022-10-01)

Extra criterial antiphospholipid antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus (preliminary data)
by: F. A. Cheldieva, et al.
Published: (2021-10-01)

Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations
by: T. Ziglioli, et al.
Published: (2011-06-01)

Retinal ischemia as the first manifestation of antiphospholipid antibody syndrome
by: Giovanna Maria Oliveira Ribeiro, et al.
Published: (2021-04-01)

Immune Thrombocytopenia Could be an Independent Clinical Phenotype of Antiphospholipid Syndrome: A Prospective Cohort Study
by: Yu Shi, et al.
Published: (2023-02-01)

Definition and treatment approach of non-criteria clinical manifestations of antiphospholipid syndrome
by: Ayten Yazıcı
Published: (2020-10-01)

The Effects of the oxLDL/β2GPI/anti‐β2GPI Complex on Macrophage Autophagy and its Mechanism
by: Qianqian Wu, et al.
Published: (2024-11-01)

Ten Rules for the Management of Antiphospholipid Syndrome
by: Jiuliang Zhao
Published: (2024-01-01)

Adrenal insufficiency as the first clinical manifestation of the primary antiphospholipid antibody syndrome.
by: Satta, M, et al.
Published: (2000)

Isolated IgA Anti-β2 Glycoprotein I Antibodies in Patients with Clinical Criteria for Antiphospholipid Syndrome
by: Raquel Ruiz-García, et al.
Published: (2014-01-01)

Antibodies to domain I β2 -glycoprotein 1 in patients with antiphospholipid syndrome and systemic lupus erythematosus
by: F. A. Cheldieva, et al.
Published: (2022-07-01)

Cryptogenic stroke and seronegative antiphospholipid syndrome: a case series of patients with positivity for “non-criteria” antiphospholipid antibodies
by: S. Mancuso, et al.
Published: (2024-09-01)

Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review
by: Yik Long Man, et al.
Published: (2022-01-01)

Non-criteria antiphospholipid antibodies and pediatric rheumatic disease: a case series
by: Shawn A. Mahmud, et al.
Published: (2022-08-01)

Role of Lipid Rafts on LRP8 Signaling Triggered by Anti-β2-GPI Antibodies in Endothelial Cells
by: Gloria Riitano, et al.
Published: (2023-11-01)

Mechanism of antiphospholipid antibody-mediated thrombosis in antiphospholipid syndrome
by: Leiyi Yang, et al.
Published: (2025-03-01)

Interaction of antiphospholipid antibodies with endothelial cells in antiphospholipid syndrome
by: Weimin Feng, et al.
Published: (2024-07-01)

Antiphospholipid Syndrome and Antibodies
by: Jozélio Freire de Carvalho, et al.
Published: (2014-01-01)

New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats
by: Paolo Durigutto, et al.
Published: (2019-04-01)

Liver infarctions as the first manifestation of antiphospholipid antibody syndrome in pregnancy: a case report
by: Claudia Meloni, et al.
Published: (2022-03-01)

Antiphospholipid antibodies as potential predictors of disease severity and poor prognosis in systemic lupus erythematosus-associated thrombocytopenia: results from a real-world CSTAR cohort study
by: Jun Li, et al.
Published: (2024-03-01)

Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies
by: Daniel Álvarez, et al.
Published: (2024-01-01)

Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management
by: Pasquale Pignatelli, et al.
Published: (2020-03-01)