Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial
Background: Awareness during anesthesia is a major anesthetic concern. Depth of anesthesia is commonly assessed in clinical practice by the patient’s clinical signs and symptoms such as blood pressure, heart rate variability, and body movement. At present, many studies have focused on qCON monitorin...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2024-03-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/59955 |
| _version_ | 1797288548275060736 |
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| author | Himalaya Dutta Suchismita Mallick Baisakhi Laha Sarbari Swaika Uday Sankar Mandal Sarmila Ghosh |
| author_facet | Himalaya Dutta Suchismita Mallick Baisakhi Laha Sarbari Swaika Uday Sankar Mandal Sarmila Ghosh |
| author_sort | Himalaya Dutta |
| collection | DOAJ |
| description | Background: Awareness during anesthesia is a major anesthetic concern. Depth of anesthesia is commonly assessed in clinical practice by the patient’s clinical signs and symptoms such as blood pressure, heart rate variability, and body movement. At present, many studies have focused on qCON monitoring for sedative depth, but only a few studies have focused on qNOX monitoring for analgesic depth.
Aims and Objectives: The aim of the present study was to evaluate the relative efficacy of qCON and qNOX versus commonly used vital signs such as blood pressure and heart rate in monitoring the anesthetic depth and analgesia.
Materials and Methods: A total of 100 patients of either sex and of ASA Physical status I & II, scheduled for urogenital surgeries, were selected and randomly placed into two groups. Group A was monitored by conventional clinical technique and Group B was monitored by qCON and qNOX indices. The primary outcome was the total dose of propofol and fentanyl required to maintain the depth of anesthesia and analgesia. The secondary outcomes were propofol and fentanyl adjustment frequency, infusion duration, and quality of recovery from anesthesia.
Results: Results showed statistically significant differences between the two groups in mean dose of both propofol (P=0.000) and fentanyl (P=0.006), adjustment frequency of both propofol (P=0.000) and fentanyl (P=0.010), time required to voluntary eye-opening (P=0.000) and extubation time (P=0.000) and visual analog scale score (P=0.000). There was no statistically significant difference found in infusion duration (P=0.317) and Ramsay Sedation Score (P=0.709) between the groups.
Conclusion: Using the qCON and qNOX indices, an anesthesiologist can monitor the depth of anesthesia and analgesia more effectively and can adjust the anesthetic or analgesic drug dosing in a better possible way with lesser requirement of drugs than with conventional clinical monitoring. |
| first_indexed | 2024-03-07T18:51:06Z |
| format | Article |
| id | doaj.art-26a3c7bc2e894a1c94694b1d67226e8e |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-07T18:51:06Z |
| publishDate | 2024-03-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-26a3c7bc2e894a1c94694b1d67226e8e2024-03-02T01:19:27ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762024-03-011532025https://doi.org/10.3126/ajms.v15i3.59955Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trialHimalaya Dutta 0https://orcid.org/0009-0007-0274-7326Suchismita Mallick 1https://orcid.org/0000-0001-9913-0080Baisakhi Laha 2https://orcid.org/0000-0002-6260-020XSarbari Swaika 3https://orcid.org/0000-0002-0525-8460Uday Sankar Mandal 4https://orcid.org/0000-0002-2886-8333Sarmila Ghosh 5https://orcid.org/0009-0007-0568-4930Senior Resident, Department of Anaesthesiology, Barasat Government Medical College and Hospital, Barasat, Kolkata, West Bengal, India Associate Professor, Department of Anaesthesiology, Deben Mahata Government Medical College and Hospital, Purulia, West Bengal, India Associate Professor, Department of Anaesthesiology, IPGME&R, Kolkata, West Bengal, India Professor and Head, Department of Emergency Medicine, IPGME&R, Kolkata, West Bengal, India Associate Professor, Department of Psychiatry, Bankura Sammilani Medical College, Bankura, West Bengal, India Professor, Department of Anaesthesiology, Murshidabad Medical College, Murshidabad, West Bengal, India Background: Awareness during anesthesia is a major anesthetic concern. Depth of anesthesia is commonly assessed in clinical practice by the patient’s clinical signs and symptoms such as blood pressure, heart rate variability, and body movement. At present, many studies have focused on qCON monitoring for sedative depth, but only a few studies have focused on qNOX monitoring for analgesic depth. Aims and Objectives: The aim of the present study was to evaluate the relative efficacy of qCON and qNOX versus commonly used vital signs such as blood pressure and heart rate in monitoring the anesthetic depth and analgesia. Materials and Methods: A total of 100 patients of either sex and of ASA Physical status I & II, scheduled for urogenital surgeries, were selected and randomly placed into two groups. Group A was monitored by conventional clinical technique and Group B was monitored by qCON and qNOX indices. The primary outcome was the total dose of propofol and fentanyl required to maintain the depth of anesthesia and analgesia. The secondary outcomes were propofol and fentanyl adjustment frequency, infusion duration, and quality of recovery from anesthesia. Results: Results showed statistically significant differences between the two groups in mean dose of both propofol (P=0.000) and fentanyl (P=0.006), adjustment frequency of both propofol (P=0.000) and fentanyl (P=0.010), time required to voluntary eye-opening (P=0.000) and extubation time (P=0.000) and visual analog scale score (P=0.000). There was no statistically significant difference found in infusion duration (P=0.317) and Ramsay Sedation Score (P=0.709) between the groups. Conclusion: Using the qCON and qNOX indices, an anesthesiologist can monitor the depth of anesthesia and analgesia more effectively and can adjust the anesthetic or analgesic drug dosing in a better possible way with lesser requirement of drugs than with conventional clinical monitoring.https://www.nepjol.info/index.php/AJMS/article/view/59955conox monitor; depth of anesthesia; extubation time; propofol; fentanyl |
| spellingShingle | Himalaya Dutta Suchismita Mallick Baisakhi Laha Sarbari Swaika Uday Sankar Mandal Sarmila Ghosh Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial Asian Journal of Medical Sciences conox monitor; depth of anesthesia; extubation time; propofol; fentanyl |
| title | Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial |
| title_full | Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial |
| title_fullStr | Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial |
| title_full_unstemmed | Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial |
| title_short | Monitoring of general anesthesia by qCON and qNOX indices versus conventional clinical parameters in urological surgery: A randomized controlled clinical trial |
| title_sort | monitoring of general anesthesia by qcon and qnox indices versus conventional clinical parameters in urological surgery a randomized controlled clinical trial |
| topic | conox monitor; depth of anesthesia; extubation time; propofol; fentanyl |
| url | https://www.nepjol.info/index.php/AJMS/article/view/59955 |
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