Comparative Assessment of APTT Reagents for Evaluating Anticoagulant Sensitivity of Fucosylated Glycosaminoglycans (FGs) Derived from Sea Cucumbers

Comparative Assessment of APTT Reagents for Evaluating Anticoagulant Sensitivity of Fucosylated Glycosaminoglycans (FGs) Derived from Sea Cucumbers

Fucosylated glycosaminoglycans (FGs) derived from sea cucumbers exhibit potent intrinsic Xase (iXase) inhibition, anticoagulation, and antithrombosis. Plasma activated partial thromboplastin time (APTT), a widely used screening test worldwide, is crucial for evaluating anticoagulant efficacy. Howeve...

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Bibliographic Details
Main Authors: Huifang Sun, Shasha Yang, Pengfei Li, Xiaolei Shang, Pin Wang, Jiali Zhang, Lin Yuan, Ronghua Yin, Na Gao, Jinhua Zhao
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Marine Drugs
Subjects:
fucosylated glycosaminoglycan
intrinsic Xase inhibitor
APTT
ellagic acid
colloidal silica
Online Access:https://www.mdpi.com/1660-3397/21/11/568

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https://www.mdpi.com/1660-3397/21/11/568

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