Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM
The most common macrovascular complication of type 2 DM’s patiens is coronary artery disease caused by coronary artery stricture or spasm or both of them. The atherosclerosis process in coronary artery can be seen through coronary artery histopathology of rat. DM can be controlled so that the compli...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
University of Jember, Faculty of Medicine
2017-12-01
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Series: | Journal of Agromedicine and Medical Sciences (AMS) |
Online Access: | https://jurnal.unej.ac.id/index.php/JAMS/article/view/6165 |
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author | Monika Roosyidah Erfan Efendi Hairrudin Hairrudin |
author_facet | Monika Roosyidah Erfan Efendi Hairrudin Hairrudin |
author_sort | Monika Roosyidah |
collection | DOAJ |
description | The most common macrovascular complication of type 2 DM’s patiens is coronary artery disease caused by coronary artery stricture or spasm or both of them. The atherosclerosis process in coronary artery can be seen through coronary artery histopathology of rat. DM can be controlled so that the complication can be prevented, for example by controlling diet. Artificial rice with high fiber is one of breakthrough for DM patients diet. The purpose of this research is to know about the effects of artificial rice diet administration to coronary artery histopathology of rat model type 2 DM. Rats are divided to four groups consist of control normal group given standart feeding, PBA1;PBA2;PBB group are inducted by high fat diet and low dose STZ so that they become rat model type 2 DM. Since PBA1 is feeded by formula 1 artificial rice, PBA1 is feeded by formula 2 artificial rice and PBB is feeded by common rice. Rats are terminated and their hearts are taken away to make histopathology object and their coronary artery are seen under light microscope. Histopathology images are based on foam cell formed. Kruskal-Wallis’s result shows that p= 0,046 (p<0,05), so that there is a significant difference between groups.
Keywords : DM, atherosclerosis, foam cell, coronary artery histopathology |
first_indexed | 2024-04-10T17:41:50Z |
format | Article |
id | doaj.art-26a5db5efb34446881ede58326a7b871 |
institution | Directory Open Access Journal |
issn | 2460-9048 2714-5654 |
language | English |
last_indexed | 2024-04-10T17:41:50Z |
publishDate | 2017-12-01 |
publisher | University of Jember, Faculty of Medicine |
record_format | Article |
series | Journal of Agromedicine and Medical Sciences (AMS) |
spelling | doaj.art-26a5db5efb34446881ede58326a7b8712023-02-03T12:18:35ZengUniversity of Jember, Faculty of MedicineJournal of Agromedicine and Medical Sciences (AMS)2460-90482714-56542017-12-0133444910.19184/ams.v3i3.61656165Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DMMonika RoosyidahErfan EfendiHairrudin HairrudinThe most common macrovascular complication of type 2 DM’s patiens is coronary artery disease caused by coronary artery stricture or spasm or both of them. The atherosclerosis process in coronary artery can be seen through coronary artery histopathology of rat. DM can be controlled so that the complication can be prevented, for example by controlling diet. Artificial rice with high fiber is one of breakthrough for DM patients diet. The purpose of this research is to know about the effects of artificial rice diet administration to coronary artery histopathology of rat model type 2 DM. Rats are divided to four groups consist of control normal group given standart feeding, PBA1;PBA2;PBB group are inducted by high fat diet and low dose STZ so that they become rat model type 2 DM. Since PBA1 is feeded by formula 1 artificial rice, PBA1 is feeded by formula 2 artificial rice and PBB is feeded by common rice. Rats are terminated and their hearts are taken away to make histopathology object and their coronary artery are seen under light microscope. Histopathology images are based on foam cell formed. Kruskal-Wallis’s result shows that p= 0,046 (p<0,05), so that there is a significant difference between groups. Keywords : DM, atherosclerosis, foam cell, coronary artery histopathologyhttps://jurnal.unej.ac.id/index.php/JAMS/article/view/6165 |
spellingShingle | Monika Roosyidah Erfan Efendi Hairrudin Hairrudin Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM Journal of Agromedicine and Medical Sciences (AMS) |
title | Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM |
title_full | Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM |
title_fullStr | Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM |
title_full_unstemmed | Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM |
title_short | Effect Artificial Rice Diet Administration to Coronary Artery Histopathology of Rat Model Type 2 DM |
title_sort | effect artificial rice diet administration to coronary artery histopathology of rat model type 2 dm |
url | https://jurnal.unej.ac.id/index.php/JAMS/article/view/6165 |
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