Developing a Vaccine to Block West Nile Virus Transmission: In Silico Studies, Molecular Characterization, Expression, and Blocking Activity of <i>Culex pipiens</i> mosGCTL-1

Developing a Vaccine to Block West Nile Virus Transmission: In Silico Studies, Molecular Characterization, Expression, and Blocking Activity of <i>Culex pipiens</i> mosGCTL-1

Background: Mosquito galactose-specific C-type lectins (mosGCTLs), such as mosGCTL-1, act as ligands to facilitate the invasion of flaviviruses like West Nile virus (WNV). WNV interacts with the <i>mosGCTL-1</i> of <i>Aedes aegypti</i> (Culicidae) and facilitates the invasion...

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Bibliographic Details
Main Authors: Hasan Bakhshi, Mehdi Fazlalipour, Javad Dadgar-Pakdel, Sedigheh Zakeri, Abbasali Raz, Anna-Bella Failloux, Navid Dinparast Djadid
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pathogens
Subjects:
<i>Culex pipiens</i>
<i>mosGCTL-1</i>
transmission blocking vaccine
West Nile virus
Online Access:https://www.mdpi.com/2076-0817/10/2/218

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