RNA-Seq for enrichment and analysis of IRF5 transcript expression in SLE.

RNA-Seq for enrichment and analysis of IRF5 transcript expression in SLE.

Polymorphisms in the interferon regulatory factor 5 (IRF5) gene have been consistently replicated and shown to confer risk for or protection from the development of systemic lupus erythematosus (SLE). IRF5 expression is significantly upregulated in SLE patients and upregulation associates with IRF5-...

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Bibliographic Details
Main Authors: Rivka C Stone, Peicheng Du, Di Feng, Kopal Dhawan, Lars Rönnblom, Maija-Leena Eloranta, Robert Donnelly, Betsy J Barnes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3548774?pdf=render

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