Gut-microbiome-brain axis: the crosstalk between the vagus nerve, alpha-synuclein and the brain in Parkinson’s disease
This critical review of the literature shows that there is a close link between the microbiome, the gut, and the brain in Parkinson’s disease. The vagus nerve, the main component of the parasympathetic nervous system, is involved in the regulation of immune response, digestion, heart rate, and contr...
Main Authors: | Júlio César Claudino dos Santos, Leandro Freitas Oliveira, Felipe Micelli Noleto, Camilla Teixeira Pinheiro Gusmão, Gerly Anne de Castro Brito, Glauce Socorro de Barros Viana |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2023-01-01
|
Series: | Neural Regeneration Research |
Subjects: | |
Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=12;spage=2611;epage=2614;aulast=Claudino |
Similar Items
-
Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
by: Norihito Uemura, et al.
Published: (2018-05-01) -
Gut-to-Brain α-Synuclein Transmission in Parkinson’s Disease: Evidence for Prion-like Mechanisms
by: Merry Chen, et al.
Published: (2023-04-01) -
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models
by: Rachel Kelly, et al.
Published: (2021-11-01) -
Gastroparesis in Parkinson Disease: Pathophysiology, and Clinical Management
by: Heithem Soliman, et al.
Published: (2021-06-01) -
The Role of Lipids in the Initiation of α-Synuclein Misfolding
by: Martin Kiechle, et al.
Published: (2020-09-01)