Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020
Hepatitis E virus (HEV) is the major cause of acute viral hepatitis in several countries in Europe. HEV is acquired mainly by consumption of contaminated pork but can also be transmitted through blood transfusion. HEV infection is usually self-limited but can become persistent in immunocompromised...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2022-01-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/28/1/21-1466_article |
| _version_ | 1797687239975632896 |
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| author | Marta Bes Maria I. Costafreda Mar Riveiro-Barciela Maria Piron Angie Rico Josep Quer Lluis Puig Silvia Sauleda |
| author_facet | Marta Bes Maria I. Costafreda Mar Riveiro-Barciela Maria Piron Angie Rico Josep Quer Lluis Puig Silvia Sauleda |
| author_sort | Marta Bes |
| collection | DOAJ |
| description |
Hepatitis E virus (HEV) is the major cause of acute viral hepatitis in several countries in Europe. HEV is acquired mainly by consumption of contaminated pork but can also be transmitted through blood transfusion. HEV infection is usually self-limited but can become persistent in immunocompromised persons. During the first 30 months of HEV RNA universal screening of blood donations in Catalonia, Spain, we identified 151 HEV RNA–positive donations (1/4,341 blood donations). Most infected donors reported consumption of pates and sausages, and 58% were negative for HEV IgM and IgG. All HEV isolates belonged to genotype 3. All infected donors spontaneously resolved the infection, and no neurologic symptoms and reinfections were observed after 1 year of follow-up. Since the implementation of HEV RNA universal screening, no new cases of transfusion-transmitted HEV infection were reported. Our data indicate HEV screening of blood donations provides safer blood for all recipients, especially for immunosuppressed persons.
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| first_indexed | 2024-03-12T01:16:22Z |
| format | Article |
| id | doaj.art-26b0fb3dafb140a996567056368a4060 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-03-12T01:16:22Z |
| publishDate | 2022-01-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-26b0fb3dafb140a996567056368a40602023-09-13T11:40:20ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592022-01-0128115716510.3201/eid2801.211466Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020Marta BesMaria I. CostafredaMar Riveiro-BarcielaMaria PironAngie RicoJosep QuerLluis PuigSilvia Sauleda Hepatitis E virus (HEV) is the major cause of acute viral hepatitis in several countries in Europe. HEV is acquired mainly by consumption of contaminated pork but can also be transmitted through blood transfusion. HEV infection is usually self-limited but can become persistent in immunocompromised persons. During the first 30 months of HEV RNA universal screening of blood donations in Catalonia, Spain, we identified 151 HEV RNA–positive donations (1/4,341 blood donations). Most infected donors reported consumption of pates and sausages, and 58% were negative for HEV IgM and IgG. All HEV isolates belonged to genotype 3. All infected donors spontaneously resolved the infection, and no neurologic symptoms and reinfections were observed after 1 year of follow-up. Since the implementation of HEV RNA universal screening, no new cases of transfusion-transmitted HEV infection were reported. Our data indicate HEV screening of blood donations provides safer blood for all recipients, especially for immunosuppressed persons. https://wwwnc.cdc.gov/eid/article/28/1/21-1466_articlehepatitis E virusHEVvirusesvirus RNAviral loaduniversal blood donor screening |
| spellingShingle | Marta Bes Maria I. Costafreda Mar Riveiro-Barciela Maria Piron Angie Rico Josep Quer Lluis Puig Silvia Sauleda Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 Emerging Infectious Diseases hepatitis E virus HEV viruses virus RNA viral load universal blood donor screening |
| title | Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 |
| title_full | Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 |
| title_fullStr | Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 |
| title_full_unstemmed | Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 |
| title_short | Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017‒2020 |
| title_sort | effect of hepatitis e virus rna universal blood donor screening catalonia spain 2017 2020 |
| topic | hepatitis E virus HEV viruses virus RNA viral load universal blood donor screening |
| url | https://wwwnc.cdc.gov/eid/article/28/1/21-1466_article |
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