Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis Lesions and Its Involvement in Oligodendroglial Stress Responses

Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis Lesions and Its Involvement in Oligodendroglial Stress Responses

This study comprehensively addresses the involvement of the protein CKLF-like Marvel transmembrane domain-containing family member 5 (CMTM5) in the context of demyelination and cytodegenerative autoimmune diseases, particularly multiple Sclerosis (MS). An observed reduction in CMTM5 expression in po...

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Bibliographic Details
Main Authors: Jiangshan Zhan, Yuanxu Gao, Leo Heinig, Malena Beecken, Yangbo Huo, Wansong Zhang, Pingzhang Wang, Tianzi Wei, Ruilin Tian, Wenling Han, Albert Cheung Hoi Yu, Markus Kipp, Hannes Kaddatz
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
CMTM5
multiple sclerosis
cuprizone
experimental autoimmune encephalomyelitis
demyelination
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2073-4409/12/16/2085

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