Recent advances in corneal collagen cross-linking
Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=9;spage=787;epage=796;aulast=Sachdev |
| _version_ | 1818278531879141376 |
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| author | Gitansha Shreyas Sachdev Mahipal Sachdev |
| author_facet | Gitansha Shreyas Sachdev Mahipal Sachdev |
| author_sort | Gitansha Shreyas Sachdev |
| collection | DOAJ |
| description | Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide implications in the form of accelerated and pulsed protocols. Newer advancements in technology include various riboflavin formulations and the ability to deliver higher fluence protocols with customised irradiation patterns. A greater degree of customisation is likely the path forward, which will aim at achieving refractive improvements along with disease stability. The use of cross-linking for myopic correction is another avenue under exploration. Combination of half fluence cross-linking with refractive correction for high errors to prevent post LASIK regression is gaining interest. This review aims to highlight the various advancements in the cross-linking technology and its clinical applications. |
| first_indexed | 2024-12-12T23:18:55Z |
| format | Article |
| id | doaj.art-26b3370e9bab45f1a896d20cd34faf1f |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-12T23:18:55Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-26b3370e9bab45f1a896d20cd34faf1f2022-12-22T00:08:20ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892017-01-0165978779610.4103/ijo.IJO_648_17Recent advances in corneal collagen cross-linkingGitansha Shreyas SachdevMahipal SachdevCorneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide implications in the form of accelerated and pulsed protocols. Newer advancements in technology include various riboflavin formulations and the ability to deliver higher fluence protocols with customised irradiation patterns. A greater degree of customisation is likely the path forward, which will aim at achieving refractive improvements along with disease stability. The use of cross-linking for myopic correction is another avenue under exploration. Combination of half fluence cross-linking with refractive correction for high errors to prevent post LASIK regression is gaining interest. This review aims to highlight the various advancements in the cross-linking technology and its clinical applications.http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=9;spage=787;epage=796;aulast=SachdevAccelerated cross-linkingcorneal collagen cross-linkingcustomized cross-linkingphotorefractive intrastromal cross-linkingpulsed cross-linking |
| spellingShingle | Gitansha Shreyas Sachdev Mahipal Sachdev Recent advances in corneal collagen cross-linking Indian Journal of Ophthalmology Accelerated cross-linking corneal collagen cross-linking customized cross-linking photorefractive intrastromal cross-linking pulsed cross-linking |
| title | Recent advances in corneal collagen cross-linking |
| title_full | Recent advances in corneal collagen cross-linking |
| title_fullStr | Recent advances in corneal collagen cross-linking |
| title_full_unstemmed | Recent advances in corneal collagen cross-linking |
| title_short | Recent advances in corneal collagen cross-linking |
| title_sort | recent advances in corneal collagen cross linking |
| topic | Accelerated cross-linking corneal collagen cross-linking customized cross-linking photorefractive intrastromal cross-linking pulsed cross-linking |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=9;spage=787;epage=796;aulast=Sachdev |
| work_keys_str_mv | AT gitanshashreyassachdev recentadvancesincornealcollagencrosslinking AT mahipalsachdev recentadvancesincornealcollagencrosslinking |