Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia

We report a case of a rare and sypmtomatic familyal hypercholesterolemia case with an end-point of coronary artery bypass surgery at the age of 16. Patient was evaluated at the emergency department with chest pain and discomfort. Physical examination were within normal limits. The electrocardiogram...

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Main Authors: Sureyya Talay, Burcin Abud
Format: Article
Language:English
Published: Cukurova University 2014-08-01
Series:Çukurova Üniversitesi Tıp Fakültesi Dergisi
Subjects:
Online Access:http://www.scopemed.org/fulltextpdf.php?mno=149852
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author Sureyya Talay
Burcin Abud
author_facet Sureyya Talay
Burcin Abud
author_sort Sureyya Talay
collection DOAJ
description We report a case of a rare and sypmtomatic familyal hypercholesterolemia case with an end-point of coronary artery bypass surgery at the age of 16. Patient was evaluated at the emergency department with chest pain and discomfort. Physical examination were within normal limits. The electrocardiogram showed a normal sinus rhythm for 108/ min. Arterial blood pressure was 90/60 mmHg. Lungs and heart were clear to auscultation. Patient was under treatment with a prior diagnosis of familial hypercholesterolemia (FH) for one year by daily 40 mgs rosuvastatine. A coronary artery angiography was performed for chest pain. Multivessel coronary artery disease was diagnosed with a total occlusion of left anterior descending artery. Transthoracic echocardiography presented a left ventricular (LV) ejection fraction 50%, LV diameters 44/26 mm, aneurysm formation at interatrial septum and mild dyskinesia of anterior wall. Thus, a five vessel emergent coronary artery graft bypass surgery was performed at this early age. FH is with a severe elevation in total cholesterol (TC) and low density lipoprotein cholesterol (LDL) in an autosomal dominant characteristic disorder that approximately occurs in 1 per 500 persons by its heterozygous form. FH is most certainly associated with premature coronary artery disease (CAD) with catasthrophic early age results. [Cukurova Med J 2014; 39(4.000): 872-875]
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spelling doaj.art-26b369290d92464a855c369ddcdae5232023-02-15T16:19:58ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502014-08-01394872875149852Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial HypercholesterolemiaSureyya Talay0Burcin Abud1Canakkale State Hospital Izmir Tepecik Research and Education HospitalWe report a case of a rare and sypmtomatic familyal hypercholesterolemia case with an end-point of coronary artery bypass surgery at the age of 16. Patient was evaluated at the emergency department with chest pain and discomfort. Physical examination were within normal limits. The electrocardiogram showed a normal sinus rhythm for 108/ min. Arterial blood pressure was 90/60 mmHg. Lungs and heart were clear to auscultation. Patient was under treatment with a prior diagnosis of familial hypercholesterolemia (FH) for one year by daily 40 mgs rosuvastatine. A coronary artery angiography was performed for chest pain. Multivessel coronary artery disease was diagnosed with a total occlusion of left anterior descending artery. Transthoracic echocardiography presented a left ventricular (LV) ejection fraction 50%, LV diameters 44/26 mm, aneurysm formation at interatrial septum and mild dyskinesia of anterior wall. Thus, a five vessel emergent coronary artery graft bypass surgery was performed at this early age. FH is with a severe elevation in total cholesterol (TC) and low density lipoprotein cholesterol (LDL) in an autosomal dominant characteristic disorder that approximately occurs in 1 per 500 persons by its heterozygous form. FH is most certainly associated with premature coronary artery disease (CAD) with catasthrophic early age results. [Cukurova Med J 2014; 39(4.000): 872-875]http://www.scopemed.org/fulltextpdf.php?mno=149852Familial hypercholesterolemiacoronary artery bypass surgeryearly age
spellingShingle Sureyya Talay
Burcin Abud
Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
Çukurova Üniversitesi Tıp Fakültesi Dergisi
Familial hypercholesterolemia
coronary artery bypass surgery
early age
title Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
title_full Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
title_fullStr Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
title_full_unstemmed Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
title_short Five Vessel Coronary Arter Bypass Graft Surgery in a Case with Familial Hypercholesterolemia
title_sort five vessel coronary arter bypass graft surgery in a case with familial hypercholesterolemia
topic Familial hypercholesterolemia
coronary artery bypass surgery
early age
url http://www.scopemed.org/fulltextpdf.php?mno=149852
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