Identification of Candidate mRNA Isoforms for Prostate Cancer-Risk SNPs Utilizing Iso-eQTL and sQTL Methods

Identification of Candidate mRNA Isoforms for Prostate Cancer-Risk SNPs Utilizing Iso-eQTL and sQTL Methods

Single nucleotide polymorphisms (SNPs) impacting the alternative splicing (AS) process (sQTLs) or isoform expression (iso-eQTL) are implicated as important cancer regulatory elements. To find the sQTL and iso-eQTL, we retrieved prostate cancer (PrCa) tissue RNA-seq and genotype data originating from...

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Bibliographic Details
Main Authors: Afshin Moradi, Harsh Sharma, Ravi Datta Sharma, Achala Fernando, Roberto A. Barrero, Jyotsna Batra
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
alternative spicing
prostate cancer
Iso-eQTL
sQTL
Online Access:https://www.mdpi.com/1422-0067/23/20/12406

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