Anti-VEGFR2-interferon-α2 regulates the tumor microenvironment and exhibits potent antitumor efficacy against colorectal cancer
Interferon-α (IFNα) has multiple antitumor effects including direct antitumor toxicity and the ability to potently stimulate both innate and adaptive immunity. However, its clinical applications in the treatment of malignancies have been limited because of short half-life and serious adverse reactio...
Main Authors: | Zhaoting Li, Yijia Zhu, Chenchen Li, Ryan Trinh, Xueyan Ren, Fumou Sun, Youfu Wang, Pengzhao Shang, Tong Wang, Min Wang, Sherie L. Morrison, Juan Zhang |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-03-01
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Series: | OncoImmunology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2162402X.2017.1290038 |
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