Progressive tauopathy disrupts breathing stability and chemoreflexes during presumptive sleep in mice

Rationale: Although sleep apnea occurs in over 50% of individuals with Alzheimer’s Disease (AD) or related tauopathies, little is known concerning the potential role of tauopathy in the pathogenesis of sleep apnea. Here, we tested the hypotheses that, during presumptive sleep, a murine model of tauo...

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Bibliographic Details
Main Authors: Alexandria B. Marciante, Carter Lurk, Luz Mata, Jada Lewis, Leah R. Reznikov, Gordon S. Mitchell
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1272980/full