Blood flow CFD simulation on a cerebral artery of a stroke patient
Abstract The purpose of this paper is to conduct a numerical simulation of the stroke patient's cerebral arteries and investigate the flow parameters due to the presence of stenosis. The computational fluid dynamics (CFD) simulations are based on simplified and realistic cerebral artery models....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Springer
2022-09-01
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| Series: | SN Applied Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s42452-022-05149-y |
| _version_ | 1811273597328556032 |
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| author | Ahmed G. Rahma Khaled Yousef Talaat Abdelhamid |
| author_facet | Ahmed G. Rahma Khaled Yousef Talaat Abdelhamid |
| author_sort | Ahmed G. Rahma |
| collection | DOAJ |
| description | Abstract The purpose of this paper is to conduct a numerical simulation of the stroke patient's cerebral arteries and investigate the flow parameters due to the presence of stenosis. The computational fluid dynamics (CFD) simulations are based on simplified and realistic cerebral artery models. The seven simplified models (benchmarks) include straight cylindrical vessels with idealized stenosis with variable d/D (0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1). The realistic model of the cerebral artery is based on magnetic resonance imaging (MRI) for patient-specific cerebral arteries. The simulation for the realistic model of the cerebral artery is performed at boundary conditions measured by ultrasonography of the input and the output flow profiles (velocity and pressure). The obtained CFD results of the benchmarks are validated with actual data from the literature. Furthermore, a previous vascular contraction is assumed to be exist and the effect of this contraction area ratio on the blood flow regime is discussed and highlighted. Furthermore, CFD results show that a certain vascular contraction area critically affects the blood flow which shows increasing the wall shear stress WSS at the stenosis site. An increase in the blood velocity and vortex appears after the contraction zone, this lead to vessel occlusion and strokes. Article highlights The pressure drop across the arterial contraction is reduced when the area ratio d/D is increased. In some cases, the vortex can prevent blood flow from crossing, this leads to vessel occlusion especially at low d/D The WSS near the contraction area is high. Increasing the WSS can cause embolism that leads to lead to vessel occlusion. |
| first_indexed | 2024-04-12T23:02:07Z |
| format | Article |
| id | doaj.art-26be78b5d98845989c6620d3363a603d |
| institution | Directory Open Access Journal |
| issn | 2523-3963 2523-3971 |
| language | English |
| last_indexed | 2024-04-12T23:02:07Z |
| publishDate | 2022-09-01 |
| publisher | Springer |
| record_format | Article |
| series | SN Applied Sciences |
| spelling | doaj.art-26be78b5d98845989c6620d3363a603d2022-12-22T03:13:00ZengSpringerSN Applied Sciences2523-39632523-39712022-09-0141011210.1007/s42452-022-05149-yBlood flow CFD simulation on a cerebral artery of a stroke patientAhmed G. Rahma0Khaled Yousef1Talaat Abdelhamid2Physics and Mathematical Engineering Department, Faculty of Electronic Engineering, Menoufiya UniversityMechanical Power Engineering Dept. Faculty of Engineering, Menoufia UniversityPhysics and Mathematical Engineering Department, Faculty of Electronic Engineering, Menoufiya UniversityAbstract The purpose of this paper is to conduct a numerical simulation of the stroke patient's cerebral arteries and investigate the flow parameters due to the presence of stenosis. The computational fluid dynamics (CFD) simulations are based on simplified and realistic cerebral artery models. The seven simplified models (benchmarks) include straight cylindrical vessels with idealized stenosis with variable d/D (0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1). The realistic model of the cerebral artery is based on magnetic resonance imaging (MRI) for patient-specific cerebral arteries. The simulation for the realistic model of the cerebral artery is performed at boundary conditions measured by ultrasonography of the input and the output flow profiles (velocity and pressure). The obtained CFD results of the benchmarks are validated with actual data from the literature. Furthermore, a previous vascular contraction is assumed to be exist and the effect of this contraction area ratio on the blood flow regime is discussed and highlighted. Furthermore, CFD results show that a certain vascular contraction area critically affects the blood flow which shows increasing the wall shear stress WSS at the stenosis site. An increase in the blood velocity and vortex appears after the contraction zone, this lead to vessel occlusion and strokes. Article highlights The pressure drop across the arterial contraction is reduced when the area ratio d/D is increased. In some cases, the vortex can prevent blood flow from crossing, this leads to vessel occlusion especially at low d/D The WSS near the contraction area is high. Increasing the WSS can cause embolism that leads to lead to vessel occlusion.https://doi.org/10.1007/s42452-022-05149-yHemodynamicsCerebral arteries stenosisComputational fluid dynamicsWall shear stress |
| spellingShingle | Ahmed G. Rahma Khaled Yousef Talaat Abdelhamid Blood flow CFD simulation on a cerebral artery of a stroke patient SN Applied Sciences Hemodynamics Cerebral arteries stenosis Computational fluid dynamics Wall shear stress |
| title | Blood flow CFD simulation on a cerebral artery of a stroke patient |
| title_full | Blood flow CFD simulation on a cerebral artery of a stroke patient |
| title_fullStr | Blood flow CFD simulation on a cerebral artery of a stroke patient |
| title_full_unstemmed | Blood flow CFD simulation on a cerebral artery of a stroke patient |
| title_short | Blood flow CFD simulation on a cerebral artery of a stroke patient |
| title_sort | blood flow cfd simulation on a cerebral artery of a stroke patient |
| topic | Hemodynamics Cerebral arteries stenosis Computational fluid dynamics Wall shear stress |
| url | https://doi.org/10.1007/s42452-022-05149-y |
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