Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
Some azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising too...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Sciendo
2019-09-01
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Series: | Journal of Veterinary Research |
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Online Access: | https://doi.org/10.2478/jvetres-2019-0044 |
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author | Pietruk Konrad Piątkowska Marta Olejnik Małgorzata |
author_facet | Pietruk Konrad Piątkowska Marta Olejnik Małgorzata |
author_sort | Pietruk Konrad |
collection | DOAJ |
description | Some azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising tool to study the transformation mechanisms of xenobiotics such as azo dyes. The aim of the study was to investigate emulation of how azo dyes are enzymatically transformed to amines with EC–MS. |
first_indexed | 2024-12-22T13:23:06Z |
format | Article |
id | doaj.art-26c2cd1fd09d453282807cfe1630cec4 |
institution | Directory Open Access Journal |
issn | 2450-8608 |
language | English |
last_indexed | 2024-12-22T13:23:06Z |
publishDate | 2019-09-01 |
publisher | Sciendo |
record_format | Article |
series | Journal of Veterinary Research |
spelling | doaj.art-26c2cd1fd09d453282807cfe1630cec42022-12-21T18:24:25ZengSciendoJournal of Veterinary Research2450-86082019-09-0163343343810.2478/jvetres-2019-0044jvetres-2019-0044Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic productsPietruk Konrad0Piątkowska Marta1Olejnik Małgorzata2Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandSome azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising tool to study the transformation mechanisms of xenobiotics such as azo dyes. The aim of the study was to investigate emulation of how azo dyes are enzymatically transformed to amines with EC–MS.https://doi.org/10.2478/jvetres-2019-0044azo dyesred-oxbiomimetics3rreplacement |
spellingShingle | Pietruk Konrad Piątkowska Marta Olejnik Małgorzata Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products Journal of Veterinary Research azo dyes red-ox biomimetics 3r replacement |
title | Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
title_full | Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
title_fullStr | Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
title_full_unstemmed | Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
title_short | Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
title_sort | electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products |
topic | azo dyes red-ox biomimetics 3r replacement |
url | https://doi.org/10.2478/jvetres-2019-0044 |
work_keys_str_mv | AT pietrukkonrad electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts AT piatkowskamarta electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts AT olejnikmałgorzata electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts |