Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products

Some azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising too...

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Main Authors: Pietruk Konrad, Piątkowska Marta, Olejnik Małgorzata
Format: Article
Language:English
Published: Sciendo 2019-09-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2019-0044
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author Pietruk Konrad
Piątkowska Marta
Olejnik Małgorzata
author_facet Pietruk Konrad
Piątkowska Marta
Olejnik Małgorzata
author_sort Pietruk Konrad
collection DOAJ
description Some azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising tool to study the transformation mechanisms of xenobiotics such as azo dyes. The aim of the study was to investigate emulation of how azo dyes are enzymatically transformed to amines with EC–MS.
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spelling doaj.art-26c2cd1fd09d453282807cfe1630cec42022-12-21T18:24:25ZengSciendoJournal of Veterinary Research2450-86082019-09-0163343343810.2478/jvetres-2019-0044jvetres-2019-0044Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic productsPietruk Konrad0Piątkowska Marta1Olejnik Małgorzata2Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100Puławy, PolandSome azo dyes, including Sudans I–IV and Para Red, are genotoxic and may be biotransformed to cancerogenic aromatic amines. They are banned as food and feed additives, but their presence has been detected in food. Aromatic amines are also considered potentially toxic. Online EC–MS is a promising tool to study the transformation mechanisms of xenobiotics such as azo dyes. The aim of the study was to investigate emulation of how azo dyes are enzymatically transformed to amines with EC–MS.https://doi.org/10.2478/jvetres-2019-0044azo dyesred-oxbiomimetics3rreplacement
spellingShingle Pietruk Konrad
Piątkowska Marta
Olejnik Małgorzata
Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
Journal of Veterinary Research
azo dyes
red-ox
biomimetics
3r
replacement
title Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
title_full Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
title_fullStr Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
title_full_unstemmed Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
title_short Electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
title_sort electrochemical reduction of azo dyes mimicking their biotransformation to more toxic products
topic azo dyes
red-ox
biomimetics
3r
replacement
url https://doi.org/10.2478/jvetres-2019-0044
work_keys_str_mv AT pietrukkonrad electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts
AT piatkowskamarta electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts
AT olejnikmałgorzata electrochemicalreductionofazodyesmimickingtheirbiotransformationtomoretoxicproducts