Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study
BackgroundThis study aimed to compare the consistency of anesthesia consciousness index (Ai) with that of bispectral index (BIS) in monitoring the depth of anesthesia (DOA) during sevoflurane anesthesia, to reveal the optimal cutoff values in different states of consciousness, and explore the stabil...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
|
| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1084462/full |
| _version_ | 1811157799590166528 |
|---|---|
| author | Jian Zhan Jian Zhan Feng Chen Zhuoxi Wu Zhenxin Duan Qiangting Deng Jun Zeng Lihong Hou Jun Zhang Yongyu Si Kexuan Liu Mingjun Wang Hong Li |
| author_facet | Jian Zhan Jian Zhan Feng Chen Zhuoxi Wu Zhenxin Duan Qiangting Deng Jun Zeng Lihong Hou Jun Zhang Yongyu Si Kexuan Liu Mingjun Wang Hong Li |
| author_sort | Jian Zhan |
| collection | DOAJ |
| description | BackgroundThis study aimed to compare the consistency of anesthesia consciousness index (Ai) with that of bispectral index (BIS) in monitoring the depth of anesthesia (DOA) during sevoflurane anesthesia, to reveal the optimal cutoff values in different states of consciousness, and explore the stability of DOA monitoring during intraoperative injurious stimulation.MethodsWe enrolled 145 patients (97 men and 48 women) from 10 medical centers. General anesthesia was induced using intravenous anesthetics and maintained with sevoflurane. Ai and BIS values were recorded.ResultsThe mean difference between the Ai and BIS was-0.1747 (95% confidence interval, −0.6660 to 0.3166; p = 0.4857). The regression equation of Ai and BIS from the Deming regression analysis was y = 5.6387 + 0.9067x (y is BIS, x is Ai), and the slope and intercept were statistically significant. Meanwhile, the receiver operating characteristic curve analysis of anesthesia-induced unconsciousness, loss of consciousness, and recovery of consciousness revealed that the accuracy of Ai and BIS were similar. In addition, the optimal cutoff values of the different states of consciousness were not sensitive to age, and both Ai and BIS had no correlation with hemodynamics.ConclusionWe conclude that Ai and BIS show no systematic deviation in readings with high consistency, similar accuracy, and good stability; these insights provide more data for clinical application. |
| first_indexed | 2024-04-10T05:12:24Z |
| format | Article |
| id | doaj.art-26cbeebeb3ba4cdb86d6bdfb8b162bb5 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-10T05:12:24Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-26cbeebeb3ba4cdb86d6bdfb8b162bb52023-03-09T05:57:51ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-03-011510.3389/fnagi.2023.10844621084462Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical studyJian Zhan0Jian Zhan1Feng Chen2Zhuoxi Wu3Zhenxin Duan4Qiangting Deng5Jun Zeng6Lihong Hou7Jun Zhang8Yongyu Si9Kexuan Liu10Mingjun Wang11Hong Li12Department of Anesthesiology, Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Anesthesiology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Army Medical University, Chongqing, ChinaEditorial Office of Journal of Army Medical University, Army Medical University, Chongqing, ChinaDepartment of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, ChinaDepartment of Anesthesiology, Xijing Hospital of Air Force Military Medical University, Xi’an, Shanxi, ChinaDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Kunming Medical University, Kunming, ChinaDepartment of Anesthesiology, Nanfang Hospital of Southern Medical University, Guangzhou, ChinaDepartment of Anesthesiology, Chinese People’s Liberation Army General Hospital, Beijing, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Army Medical University, Chongqing, ChinaBackgroundThis study aimed to compare the consistency of anesthesia consciousness index (Ai) with that of bispectral index (BIS) in monitoring the depth of anesthesia (DOA) during sevoflurane anesthesia, to reveal the optimal cutoff values in different states of consciousness, and explore the stability of DOA monitoring during intraoperative injurious stimulation.MethodsWe enrolled 145 patients (97 men and 48 women) from 10 medical centers. General anesthesia was induced using intravenous anesthetics and maintained with sevoflurane. Ai and BIS values were recorded.ResultsThe mean difference between the Ai and BIS was-0.1747 (95% confidence interval, −0.6660 to 0.3166; p = 0.4857). The regression equation of Ai and BIS from the Deming regression analysis was y = 5.6387 + 0.9067x (y is BIS, x is Ai), and the slope and intercept were statistically significant. Meanwhile, the receiver operating characteristic curve analysis of anesthesia-induced unconsciousness, loss of consciousness, and recovery of consciousness revealed that the accuracy of Ai and BIS were similar. In addition, the optimal cutoff values of the different states of consciousness were not sensitive to age, and both Ai and BIS had no correlation with hemodynamics.ConclusionWe conclude that Ai and BIS show no systematic deviation in readings with high consistency, similar accuracy, and good stability; these insights provide more data for clinical application.https://www.frontiersin.org/articles/10.3389/fnagi.2023.1084462/fulldepth of anesthesiaanesthesia consciousness indexbispectral indexsevofluraneconsistency |
| spellingShingle | Jian Zhan Jian Zhan Feng Chen Zhuoxi Wu Zhenxin Duan Qiangting Deng Jun Zeng Lihong Hou Jun Zhang Yongyu Si Kexuan Liu Mingjun Wang Hong Li Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study Frontiers in Aging Neuroscience depth of anesthesia anesthesia consciousness index bispectral index sevoflurane consistency |
| title | Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study |
| title_full | Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study |
| title_fullStr | Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study |
| title_full_unstemmed | Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study |
| title_short | Consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia: A prospective multi-center randomized controlled clinical study |
| title_sort | consistency of the anesthesia consciousness index versus the bispectral index during laparoscopic gastrointestinal surgery with sevoflurane anesthesia a prospective multi center randomized controlled clinical study |
| topic | depth of anesthesia anesthesia consciousness index bispectral index sevoflurane consistency |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1084462/full |
| work_keys_str_mv | AT jianzhan consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT jianzhan consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT fengchen consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT zhuoxiwu consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT zhenxinduan consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT qiangtingdeng consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT junzeng consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT lihonghou consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT junzhang consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT yongyusi consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT kexuanliu consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT mingjunwang consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy AT hongli consistencyoftheanesthesiaconsciousnessindexversusthebispectralindexduringlaparoscopicgastrointestinalsurgerywithsevofluraneanesthesiaaprospectivemulticenterrandomizedcontrolledclinicalstudy |