Differential Inflammatory-Response Kinetics of Human Keratinocytes upon Cytosolic RNA- and DNA-Fragment Induction

Differential Inflammatory-Response Kinetics of Human Keratinocytes upon Cytosolic RNA- and DNA-Fragment Induction

Keratinocytes are non-professional immune cells contributing actively to innate immune responses partially by reacting to a wide range of molecular patterns by activating pattern recognition receptors. Cytosolic nucleotide fragments as pathogen- or self-derived trigger factors are activating inflamm...

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Bibliographic Details
Main Authors: Judit Danis, Luca Janovák, Barbara Gubán, Anikó Göblös, Kornélia Szabó, Lajos Kemény, Zsuzsanna Bata-Csörgő, Márta Széll
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
cytosolic nucleotide fragments
keratinocyte
poly(I:C)
poly(dA:dT)
signal transduction pathway
interleukin-6
tumor necrosis factor α
Online Access:http://www.mdpi.com/1422-0067/19/3/774

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http://www.mdpi.com/1422-0067/19/3/774

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